A short synthesis of 2-N-hydroxy-3,4-dihydroisoquinol-2-one has been devised, which is based on the Castagnoli-Cushman reaction and 3 times more high-yielding compared to an earlier reported sequence.

Original languageEnglish
Pages (from-to)1511-1512
Number of pages2
JournalTetrahedron Letters
Volume59
Issue number15
DOIs
StatePublished - 11 Apr 2018

    Research areas

  • Castagnoli-Cushman reaction, Decarboxylation, Formaldoxime, O-Debenzylation, TRANSPORT

    Scopus subject areas

  • Drug Discovery
  • Biochemistry
  • Organic Chemistry

ID: 34632370