Summary Despite the 10 years of history of EBUS and more then 50 years of TBLB, the evidence of the usefulness of their combination or sequence are not enough till now. The aim: to compare the diagnostic efficacy of TBLB, EBUS and their combination in verification of sarcoidosis II. Design: a prospective non-randomized trial with consecutively enrolled patients from January 2018 till December 2018. Inclusion's criteria: Patients older than 18 years with the revealed pathology in the chest CT: suspicion of sarcoidosis II (coexistence of pulmonary dissemination and mediastinal lymphadenopathy). Exclusion's criteria: previously confirmed the diagnosis without the invasive procedure, contraindications to bronchoscopy and general anesthesia or inability to consent. Material and methods: 100 patients were enrolled in the trial. Patients were divided into 3 groups: group 1 (TBLB) - 50 patients, group 2 (EBUS) - 35 patients, group 3 (TBLB and EBUS) - 15 patients. TBLB and EBUS-TBNA were performed by the experienced
