C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II)

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C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II) : Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions. / Afanasenko, Anastasiia M.; Chulkova, Tatiana G.; Boyarskaya, Irina A.; Islamova, Regina M.; Legin, Anton A.; Keppler, Bernhard K.; Selivanov, Stanislav I.; Vereshchagin, Anatoly N.; Elinson, Michail N.; Haukka, Matti.

In: Journal of Organometallic Chemistry, Vol. 923, 121435, 15.09.2020.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{a1c02b08014e42268dbfeb9a76b06ec9,

title = "C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions",

abstract = "The reaction of 3,4-diaryl-1H-pyrrol-2,5-diimines with cis-dichlorobis(isonitrile)platinum(II) affords the C,N-chelated diaminocarbene platinum(II) complexes, which have been fully characterized including molecular spectroscopy, single crystal X-ray diffraction and DFT calculations. The obtained platinum(II) complexes are effective catalysts for the hydrosilylation of alkynes and alkenes. Thus, the reaction of phenylacetylene with triethoxysilane leads to the formation of α- and β-(E)-vinylsilanes, generating TON's in the range of 103 to 104 and TOF's in the range of 102 to 103 h−1. Also, the cross-linked silicones, possessing the luminescence properties, were obtained by the hydrosilylation reaction of vinyl- and hydride-containing polysiloxanes. Additionally, the efficiency of diaminocarbene platinum(II) complexes against CH1/PA-1, SW480, and A549 cancer cell lines has been demonstrated by in vitro cytotoxicity studies.",

keywords = "Anti-cancer activity, Catalysis, Diaminocarbene platinum(II) complexes, Hydrosilylation, Luminescence, PALLADIUM, CARBENE, ACYCLIC DIAMINOCARBENE, ISONITRILES, WATER",

author = "Afanasenko, {Anastasiia M.} and Chulkova, {Tatiana G.} and Boyarskaya, {Irina A.} and Islamova, {Regina M.} and Legin, {Anton A.} and Keppler, {Bernhard K.} and Selivanov, {Stanislav I.} and Vereshchagin, {Anatoly N.} and Elinson, {Michail N.} and Matti Haukka",

year = "2020",

month = sep,

day = "15",

doi = "10.1016/j.jorganchem.2020.121435",

language = "English",

volume = "923",

journal = "Journal of Organometallic Chemistry",

issn = "0022-328X",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II)

T2 - Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions

AU - Afanasenko, Anastasiia M.

AU - Chulkova, Tatiana G.

AU - Boyarskaya, Irina A.

AU - Islamova, Regina M.

AU - Legin, Anton A.

AU - Keppler, Bernhard K.

AU - Selivanov, Stanislav I.

AU - Vereshchagin, Anatoly N.

AU - Elinson, Michail N.

AU - Haukka, Matti

PY - 2020/9/15

Y1 - 2020/9/15

N2 - The reaction of 3,4-diaryl-1H-pyrrol-2,5-diimines with cis-dichlorobis(isonitrile)platinum(II) affords the C,N-chelated diaminocarbene platinum(II) complexes, which have been fully characterized including molecular spectroscopy, single crystal X-ray diffraction and DFT calculations. The obtained platinum(II) complexes are effective catalysts for the hydrosilylation of alkynes and alkenes. Thus, the reaction of phenylacetylene with triethoxysilane leads to the formation of α- and β-(E)-vinylsilanes, generating TON's in the range of 103 to 104 and TOF's in the range of 102 to 103 h−1. Also, the cross-linked silicones, possessing the luminescence properties, were obtained by the hydrosilylation reaction of vinyl- and hydride-containing polysiloxanes. Additionally, the efficiency of diaminocarbene platinum(II) complexes against CH1/PA-1, SW480, and A549 cancer cell lines has been demonstrated by in vitro cytotoxicity studies.

AB - The reaction of 3,4-diaryl-1H-pyrrol-2,5-diimines with cis-dichlorobis(isonitrile)platinum(II) affords the C,N-chelated diaminocarbene platinum(II) complexes, which have been fully characterized including molecular spectroscopy, single crystal X-ray diffraction and DFT calculations. The obtained platinum(II) complexes are effective catalysts for the hydrosilylation of alkynes and alkenes. Thus, the reaction of phenylacetylene with triethoxysilane leads to the formation of α- and β-(E)-vinylsilanes, generating TON's in the range of 103 to 104 and TOF's in the range of 102 to 103 h−1. Also, the cross-linked silicones, possessing the luminescence properties, were obtained by the hydrosilylation reaction of vinyl- and hydride-containing polysiloxanes. Additionally, the efficiency of diaminocarbene platinum(II) complexes against CH1/PA-1, SW480, and A549 cancer cell lines has been demonstrated by in vitro cytotoxicity studies.

KW - Anti-cancer activity

KW - Catalysis

KW - Diaminocarbene platinum(II) complexes

KW - Hydrosilylation

KW - Luminescence

KW - PALLADIUM

KW - CARBENE

KW - ACYCLIC DIAMINOCARBENE

KW - ISONITRILES

KW - WATER

UR - http://www.scopus.com/inward/record.url?scp=85088996483&partnerID=8YFLogxK

U2 - 10.1016/j.jorganchem.2020.121435

DO - 10.1016/j.jorganchem.2020.121435

M3 - Article

AN - SCOPUS:85088996483

VL - 923

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

SN - 0022-328X

M1 - 121435

ER -

ID: 61417750

C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions

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