TY - JOUR

T1 - Chronoamperometric and coulometric analysis with ionophore-based ionselective electrodes: A modified theory and the potassium ion assay in serum samples

AU - Kondratyeva, Yevgeniya O.

AU - Tolstopjatova, Elena G.

AU - Kirsanov, Dmitry O.

AU - Mikhelson, Konstantin N.

PY - 2020

Y1 - 2020

N2 - The behavior of the same ion-selective electrode (ISE) under three measurement modes: potentiometric,chronoamperometric and coulometric is compared using valinomycin-based K+-ISE as model system. The ISEresponse to decrease and to increase of the K+ ion activity is studied systematically. It is shown that the theoretical description of the time dependencies of current and of charge must take the concentration polarizationin consideration, and the respective equations are presented. The concentration of K+ ion in blood serumsamples is measured in the potentiometric, in the chronoamperometric and in the coulometric mode, and satisfactory results are obtained in all three cases.

AB - The behavior of the same ion-selective electrode (ISE) under three measurement modes: potentiometric,chronoamperometric and coulometric is compared using valinomycin-based K+-ISE as model system. The ISEresponse to decrease and to increase of the K+ ion activity is studied systematically. It is shown that the theoretical description of the time dependencies of current and of charge must take the concentration polarizationin consideration, and the respective equations are presented. The concentration of K+ ion in blood serumsamples is measured in the potentiometric, in the chronoamperometric and in the coulometric mode, and satisfactory results are obtained in all three cases.

M3 - Article

VL - 310

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

SN - 0925-4005

M1 - 127894

ER -