Research output: Contribution to journal › Article › peer-review
Chronic Blockade of D2 Receptors and Behavior in Low-Depressivity Rats. / Chaika, A. V.; Khusainov, D. R.; Cheretaev, I. V.; Korenyuk, I. I.; Nozdrachev, A. D.
In: Neuroscience and Behavioral Physiology, Vol. 48, No. 5, 01.06.2018, p. 564-570.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Chronic Blockade of D2 Receptors and Behavior in Low-Depressivity Rats
AU - Chaika, A. V.
AU - Khusainov, D. R.
AU - Cheretaev, I. V.
AU - Korenyuk, I. I.
AU - Nozdrachev, A. D.
PY - 2018/6/1
Y1 - 2018/6/1
N2 - This report addresses the effects of chronic blockade of D2 receptors with haloperidol on the behavior of rats with low levels of depression. Chronic blockade of D2 receptors with haloperidol (2.5 mg/kg) had a phasic prodepressant action on the behavior of rats with a low basal level of depressivity and led to the formation of a depressive state. The index of depressivity in control and experimental animals showed weekly and half-weekly rhythms characterized by phase shifts relative to each other.
AB - This report addresses the effects of chronic blockade of D2 receptors with haloperidol on the behavior of rats with low levels of depression. Chronic blockade of D2 receptors with haloperidol (2.5 mg/kg) had a phasic prodepressant action on the behavior of rats with a low basal level of depressivity and led to the formation of a depressive state. The index of depressivity in control and experimental animals showed weekly and half-weekly rhythms characterized by phase shifts relative to each other.
KW - biorhythms
KW - D2 receptors
KW - depression
KW - haloperidol
UR - http://www.scopus.com/inward/record.url?scp=85048105929&partnerID=8YFLogxK
U2 - 10.1007/s11055-018-0600-x
DO - 10.1007/s11055-018-0600-x
M3 - Article
AN - SCOPUS:85048105929
VL - 48
SP - 564
EP - 570
JO - Neuroscience and Behavioral Physiology
JF - Neuroscience and Behavioral Physiology
SN - 0097-0549
IS - 5
ER -
ID: 37012895