Abstract: The chemical composition, structure, and electrokinetic characteristics have been studied for different vitreous materials, including basic silicate glasses and those modified with iron and nickel oxides in the course of melting. The position of the isoelectric point and the value of the electrokinetic potential of monolithic particles (two-phase glasses and quartz-like glasses) and microporous samples obtained by acidic leaching have been analyzed as depending on the chemical composition and surface structure of the materials in a solution of NaCl as an indifferent electrolyte. The influence of specifically sorbable nickel ions on the electrokinetic characteristics of silicate glasses and nickel-containing vitreous materials has been investigated.