TY - JOUR

T1 - Chemical and computational strategy for design of “switchable” sorbent based on hydroxyapatite nanoparticles for dispersive micro-solid phase extraction of tetracyclines

AU - Вах, Кристина Степановна

AU - Булатов, Андрей Васильевич

AU - Осмоловская, Ольга Михайловна

AU - Вознесенский, Михаил Андреевич

AU - Бобрышева, Наталья Петровна

AU - Сюккалова, Евгения Александровна

AU - Малкова, Ксения Павловна

N1 - Publisher Copyright: © 2021 Elsevier B.V.

PY - 2021/10/5

Y1 - 2021/10/5

N2 - A challenging task in analytical chemistry is an application of renewable and natural materials for isolation of hazardous substances such as antimicrobial drugs from environmental samples. The energy-efficient scalable hydrothermal procedure to fabricate the eco-friendly “switchable” sorbent based on hydroxyapatite nanoparticles with in situ modified surface using a small amount of capping agents was developed. Sorbents characterization including the surface composition investigation via quantum-chemical calculation based on the original approach was provided. The sorbents demonstrated well expressed controllable surface switching and high values of the sorption and elution efficiency for tetracycline, oxytetracycline, and chlortetracycline achieved by simple change of the medium pH. These processes were thoroughly discussed based on the results of chemical and computational experiments. A simple and universal strategy for choosing a suitable sorbent for solid phase extraction of target analytes was proposed for the first time. It was shown that the developed eco-friendly sample preparation procedure with use of biocompatible sorbents could be applied both for removal of target analytes from sample matrix (water samples) as well as for the quantitative analytes determination after elution step. It is believed that the presented research is significant for the determination of different amphoteric analytes in wide variety of samples.

AB - A challenging task in analytical chemistry is an application of renewable and natural materials for isolation of hazardous substances such as antimicrobial drugs from environmental samples. The energy-efficient scalable hydrothermal procedure to fabricate the eco-friendly “switchable” sorbent based on hydroxyapatite nanoparticles with in situ modified surface using a small amount of capping agents was developed. Sorbents characterization including the surface composition investigation via quantum-chemical calculation based on the original approach was provided. The sorbents demonstrated well expressed controllable surface switching and high values of the sorption and elution efficiency for tetracycline, oxytetracycline, and chlortetracycline achieved by simple change of the medium pH. These processes were thoroughly discussed based on the results of chemical and computational experiments. A simple and universal strategy for choosing a suitable sorbent for solid phase extraction of target analytes was proposed for the first time. It was shown that the developed eco-friendly sample preparation procedure with use of biocompatible sorbents could be applied both for removal of target analytes from sample matrix (water samples) as well as for the quantitative analytes determination after elution step. It is believed that the presented research is significant for the determination of different amphoteric analytes in wide variety of samples.

KW - Capping agent

KW - Dispersive micro-solid phase extraction

KW - Hydroxyapatite nanoparticles

KW - Prediction

KW - Quantum-chemical calculation

KW - Tetracyclines

KW - ANTIBIOTICS

KW - AQUEOUS-SOLUTIONS

KW - NANORODS

KW - HYDROTHERMAL SYNTHESIS

KW - PERFORMANCE LIQUID-CHROMATOGRAPHY

KW - CALCIUM

KW - EFFICIENT REMOVAL

KW - HUMAN URINE

KW - MILK SAMPLES

KW - WATER

UR - http://www.scopus.com/inward/record.url?scp=85111344839&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/69647f66-517a-3bf2-8286-2fe13a414de6/

U2 - 10.1016/j.jhazmat.2021.126504

DO - 10.1016/j.jhazmat.2021.126504

M3 - Article

VL - 419

JO - Journal of Hazardous Materials

JF - Journal of Hazardous Materials

SN - 0304-3894

M1 - 126504

ER -