Research output: Contribution to journal › Article
Characterization of the gene encoding a fibrinogen-related protein expressed in Crassostrea gigas hemocytes. / Skazina, M.A.; Gorbushin, A.M.
In: Fish and Shellfish Immunology, Vol. 54, 2016, p. 586-588.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Characterization of the gene encoding a fibrinogen-related protein expressed in Crassostrea gigas hemocytes
AU - Skazina, M.A.
AU - Gorbushin, A.M.
PY - 2016
Y1 - 2016
N2 - © 2016 Elsevier Ltd. Four exons of the CgFrep1 gene (3333 bp long) encode a putative fibrinogen-related protein (324 aa) bearing a single C-terminal FBG domain. Transcripts of the gene obtained from hemocytes of different Pacific oysters show prominent individual variation based on SNP and indels of tandem repeats resulted in polymorphism of N-terminus of the putative CgFrep1 polypeptide. The polypeptide chain bears N-terminal coiled-coil region potentially acting as inter-subunit interface in the protein oligomerization. It is suggested that CgFrep1 gene encodes the oligomeric lectin composed of at least two subunits.
AB - © 2016 Elsevier Ltd. Four exons of the CgFrep1 gene (3333 bp long) encode a putative fibrinogen-related protein (324 aa) bearing a single C-terminal FBG domain. Transcripts of the gene obtained from hemocytes of different Pacific oysters show prominent individual variation based on SNP and indels of tandem repeats resulted in polymorphism of N-terminus of the putative CgFrep1 polypeptide. The polypeptide chain bears N-terminal coiled-coil region potentially acting as inter-subunit interface in the protein oligomerization. It is suggested that CgFrep1 gene encodes the oligomeric lectin composed of at least two subunits.
U2 - 10.1016/j.fsi.2016.05.017
DO - 10.1016/j.fsi.2016.05.017
M3 - Article
VL - 54
SP - 586
EP - 588
JO - Fish and Shellfish Immunology
JF - Fish and Shellfish Immunology
SN - 1050-4648
ER -
ID: 7954501