Research output: Contribution to journal › Article › peer-review
Characteristics of the response to treatment in outpatients with the first episode of schizophrenia spectrum disorders. / Chumakov, E. M. ; Petrova, N. N. ; Limankin, O. V. .
In: ВЕСТНИК САНКТ-ПЕТЕРБУРГСКОГО УНИВЕРСИТЕТА. МЕДИЦИНА, Vol. 14, No. 3, 2019, p. 216-225.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Characteristics of the response to treatment in outpatients with the first episode of schizophrenia spectrum disorders
AU - Chumakov, E. M.
AU - Petrova, N. N.
AU - Limankin, O. V.
N1 - Chumakov E. M., PetrovaN. N., Limankin O. V.Characteristics of the response to treatment in outpatients with the first episode of schizophrenia spectrum disorders. Vestnik of Saint Petersburg University. Medicine, 2019, vol. 14, issue 3, pp. 216–225.https://doi.org/10.21638/spbu11.2019.304
PY - 2019
Y1 - 2019
N2 - Identifying predictors of treatment response in patients with the first episode of schizophrenia spectrum disorders is an important issue in the field. The objective of the study was to assess the incidence of poor response to treatment and the factors that influence it in outpatients with the first episode of schizophrenia spectrum disorders. Medical records of the outpatients seeking treatment in 2017 in 3 day inpatient departments of the two districts in St. Petersburg, Russia, were examined. 73 patients diagnosed with schizophrenia spectrum disorders (ICD-10) met the criteria for the first episode (the duration of the disease is up to 5 years, the number of episodes is not more than three) and made up the study group. It has been established that up to 49 % of outpatients with the first episode of schizophrenia spectrum disorders were characterized by poor responses to antipsychotic therapy during outpatient treatment. Factors predicting a poor response to therapy may include earlier onset of illness, concomitant brain damage, and low adherence to therapy.
AB - Identifying predictors of treatment response in patients with the first episode of schizophrenia spectrum disorders is an important issue in the field. The objective of the study was to assess the incidence of poor response to treatment and the factors that influence it in outpatients with the first episode of schizophrenia spectrum disorders. Medical records of the outpatients seeking treatment in 2017 in 3 day inpatient departments of the two districts in St. Petersburg, Russia, were examined. 73 patients diagnosed with schizophrenia spectrum disorders (ICD-10) met the criteria for the first episode (the duration of the disease is up to 5 years, the number of episodes is not more than three) and made up the study group. It has been established that up to 49 % of outpatients with the first episode of schizophrenia spectrum disorders were characterized by poor responses to antipsychotic therapy during outpatient treatment. Factors predicting a poor response to therapy may include earlier onset of illness, concomitant brain damage, and low adherence to therapy.
KW - schizophrenia
KW - Schizophrenia spectrum disorders
KW - first episode
KW - treatment response
KW - outpatients
UR - https://medicine-journal.spbu.ru/article/view/4990
M3 - Article
VL - 14
SP - 216
EP - 225
JO - ВЕСТНИК САНКТ-ПЕТЕРБУРГСКОГО УНИВЕРСИТЕТА. МЕДИЦИНА
JF - ВЕСТНИК САНКТ-ПЕТЕРБУРГСКОГО УНИВЕРСИТЕТА. МЕДИЦИНА
SN - 1818-2909
IS - 3
ER -
ID: 53108995