Changes of membrane potential (MP), amplitude of action potential (AAP) and continuance of AP (CAP) of identified neurons of leech Haemopis sanguisuga have been investigated at high intracellular Na+ concentration. It has been shown that a moderate increase of intracellular Na+ concentration leads to hyperpolarization of the membrane to 15 mV and a certain increase of AAP and CAP. A further increase of [Na+]in leads to a sharp decrease of AAP and small decrease of CAP. Possible mechanisms of the phenomena described are discussed.

Original languageEnglish
Pages (from-to)456-460
Number of pages5
JournalBiofizika
Volume22
Issue number3
StatePublished - 1 Jan 1977

    Scopus subject areas

  • Medicine(all)

ID: 39919598