Cerebral mechanisms of hypoxic/ischemic postconditioning

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Cerebral mechanisms of hypoxic/ischemic postconditioning. / Vetrovoy, O. V.; Rybnikova, E. A.; Samoilov, M. O.

In: Biochemistry (Moscow), Vol. 82, No. 3, 01.03.2017, p. 392-400.

Research output: Contribution to journal › Review article › peer-review

Author

Vetrovoy, O. V. ; Rybnikova, E. A. ; Samoilov, M. O. / Cerebral mechanisms of hypoxic/ischemic postconditioning. In: Biochemistry (Moscow). 2017 ; Vol. 82, No. 3. pp. 392-400.

BibTeX

@article{5679d2c8d6d04466a233f42669715398,

title = "Cerebral mechanisms of hypoxic/ischemic postconditioning",

abstract = "This review analyzes recent data on mechanisms of cerebral hypoxia and the protective methods of hypoxic and ischemic postconditioning, as well as their interrelationship with the key mechanisms responsible for neuroprotection and neuroplasticity. Upregulation of expression of antiapoptotic factors and neurotrophins and modulation of activity of several protein kinases and transcription factors such as hypoxia-inducible factor-1 (HIF-1) are considered as the most important aspects in the neuroprotective potential of postconditioning. The presented information indicates substantial transformative promise of the noninvasive techniques of hypoxic postconditioning as well as significant similarity between the adaptive pathways activated by various postconditioning methods, which are far from being fully understood.",

keywords = "hypoxia/ischemia, hypoxic postconditioning, ischemic postconditioning, neuropathology, neuroplasticity",

author = "Vetrovoy, {O. V.} and Rybnikova, {E. A.} and Samoilov, {M. O.}",

note = "Publisher Copyright: {\textcopyright} 2017, Pleiades Publishing, Ltd.",

year = "2017",

month = mar,

day = "1",

doi = "10.1134/S000629791703018X",

language = "English",

volume = "82",

pages = "392--400",

journal = "Biochemistry (Moscow)",

issn = "0006-2979",

publisher = "МАИК {"}Наука/Интерпериодика{"}",

number = "3",

}

RIS

TY - JOUR

T1 - Cerebral mechanisms of hypoxic/ischemic postconditioning

AU - Vetrovoy, O. V.

AU - Rybnikova, E. A.

AU - Samoilov, M. O.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - This review analyzes recent data on mechanisms of cerebral hypoxia and the protective methods of hypoxic and ischemic postconditioning, as well as their interrelationship with the key mechanisms responsible for neuroprotection and neuroplasticity. Upregulation of expression of antiapoptotic factors and neurotrophins and modulation of activity of several protein kinases and transcription factors such as hypoxia-inducible factor-1 (HIF-1) are considered as the most important aspects in the neuroprotective potential of postconditioning. The presented information indicates substantial transformative promise of the noninvasive techniques of hypoxic postconditioning as well as significant similarity between the adaptive pathways activated by various postconditioning methods, which are far from being fully understood.

AB - This review analyzes recent data on mechanisms of cerebral hypoxia and the protective methods of hypoxic and ischemic postconditioning, as well as their interrelationship with the key mechanisms responsible for neuroprotection and neuroplasticity. Upregulation of expression of antiapoptotic factors and neurotrophins and modulation of activity of several protein kinases and transcription factors such as hypoxia-inducible factor-1 (HIF-1) are considered as the most important aspects in the neuroprotective potential of postconditioning. The presented information indicates substantial transformative promise of the noninvasive techniques of hypoxic postconditioning as well as significant similarity between the adaptive pathways activated by various postconditioning methods, which are far from being fully understood.

KW - hypoxia/ischemia

KW - hypoxic postconditioning

KW - ischemic postconditioning

KW - neuropathology

KW - neuroplasticity

UR - http://www.scopus.com/inward/record.url?scp=85014932992&partnerID=8YFLogxK

U2 - 10.1134/S000629791703018X

DO - 10.1134/S000629791703018X

M3 - Review article

C2 - 28320281

AN - SCOPUS:85014932992

VL - 82

SP - 392

EP - 400

JO - Biochemistry (Moscow)

JF - Biochemistry (Moscow)

SN - 0006-2979

IS - 3

ER -

ID: 97809030