Research output: Contribution to journal › Review article › peer-review
Calcium Carbide: Versatile Synthetic Applications, Green Methodology and Sustainability. / Rodygin, Konstantin S. ; Ledovskaya , Maria S. ; Voronin , Vladimir V. ; Lotsman, Kristina A. ; Ananikov, Valentine P. .
In: European Journal of Organic Chemistry, Vol. 2021, No. 1, 2020, p. 43-52.Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - Calcium Carbide: Versatile Synthetic Applications, Green Methodology and Sustainability
AU - Rodygin, Konstantin S.
AU - Ledovskaya , Maria S.
AU - Voronin , Vladimir V.
AU - Lotsman, Kristina A.
AU - Ananikov, Valentine P.
PY - 2020
Y1 - 2020
N2 - Acetylene is a key building block for organic chemistry and potentially can be involved in a diverse range of synthetic transformations. However, critical analysis of practical considerations showed that application of gaseous acetylene in regular synthetic labs encounters a number of difficulties. Safety limitations due to flammable and explosive nature of gaseous acetylene and requirements for specialized high-pressure equipment impose serious drawbacks. Typical reaction conditions involve excess of gaseous reactant, which is simply released to the atmosphere at the end of the reaction, thus generating waste and causing contamination. Calcium carbide brings a new green and sustainable wave into powerful alkyne transformations and significantly expands the repertoire of traditional acetylene chemistry. The novel trend of using calcium carbide instead of gaseous acetylene is synthetically beneficial and opens a novel reactivity for the C≡C unit. This review highlights recent advances in carbide chemistry, demonstrates its advantages and prospects in term of green synthetic approach.
AB - Acetylene is a key building block for organic chemistry and potentially can be involved in a diverse range of synthetic transformations. However, critical analysis of practical considerations showed that application of gaseous acetylene in regular synthetic labs encounters a number of difficulties. Safety limitations due to flammable and explosive nature of gaseous acetylene and requirements for specialized high-pressure equipment impose serious drawbacks. Typical reaction conditions involve excess of gaseous reactant, which is simply released to the atmosphere at the end of the reaction, thus generating waste and causing contamination. Calcium carbide brings a new green and sustainable wave into powerful alkyne transformations and significantly expands the repertoire of traditional acetylene chemistry. The novel trend of using calcium carbide instead of gaseous acetylene is synthetically beneficial and opens a novel reactivity for the C≡C unit. This review highlights recent advances in carbide chemistry, demonstrates its advantages and prospects in term of green synthetic approach.
KW - Organic synthesis
KW - Green chemistry
KW - Atom‐efficiency
KW - Acetylene
KW - Calcium carbide
KW - Sustainable carbon cycle
KW - Atom-efficiency
UR - https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.202001098?af=R
UR - http://www.scopus.com/inward/record.url?scp=85091683134&partnerID=8YFLogxK
U2 - 10.1002/ejoc.202001098
DO - 10.1002/ejoc.202001098
M3 - Review article
VL - 2021
SP - 43
EP - 52
JO - European Journal of Organic Chemistry
JF - European Journal of Organic Chemistry
SN - 1434-193X
IS - 1
ER -
ID: 69912162