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Biomedical applications of capillary electrophoresis. / Kartsova, L.A.; Bessonova, E.A.

In: Russian Chemical Reviews, Vol. 84, No. 8, 2015, p. 860-874.

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Kartsova, L.A. ; Bessonova, E.A. / Biomedical applications of capillary electrophoresis. In: Russian Chemical Reviews. 2015 ; Vol. 84, No. 8. pp. 860-874.

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@article{a0e2f04d45294c8a923f5d21a9165632,
title = "Biomedical applications of capillary electrophoresis",
abstract = "{\textcopyright} 2015 Russian Academy of Sciences and Turpion Ltd.The review deals with modern analytical approaches used in capillary electrophoresis for solving medical and biological problems: search for biomarkers of various diseases and rapid diagnosis based on characteristic profiles of biologically active compounds by capillary electrophoresis with mass spectrometric detection; monitoring of the residual drugs in biological fluids for evaluating the efficiency of drug therapy; testing of the enantiomeric purity of pharmaceutical products; the use of novel materials as components of stationary and pseudo-stationary phases in capillary electrophoresis and capillary electrochromatography to increase the selectivity of separation of components of complex matrices; and identification of various on-line preconcentration techniques to reduce the detection limits of biologically active analytes. A topical trend in capillary electrophoresis required in clinical practice, viz., the design of microfluidic systems, is discussed.",
author = "L.A. Kartsova and E.A. Bessonova",
year = "2015",
doi = "10.1070/RCR4492",
language = "English",
volume = "84",
pages = "860--874",
journal = "Russian Chemical Reviews",
issn = "0036-021X",
publisher = "Turpion Ltd.",
number = "8",

}

RIS

TY - JOUR

T1 - Biomedical applications of capillary electrophoresis

AU - Kartsova, L.A.

AU - Bessonova, E.A.

PY - 2015

Y1 - 2015

N2 - © 2015 Russian Academy of Sciences and Turpion Ltd.The review deals with modern analytical approaches used in capillary electrophoresis for solving medical and biological problems: search for biomarkers of various diseases and rapid diagnosis based on characteristic profiles of biologically active compounds by capillary electrophoresis with mass spectrometric detection; monitoring of the residual drugs in biological fluids for evaluating the efficiency of drug therapy; testing of the enantiomeric purity of pharmaceutical products; the use of novel materials as components of stationary and pseudo-stationary phases in capillary electrophoresis and capillary electrochromatography to increase the selectivity of separation of components of complex matrices; and identification of various on-line preconcentration techniques to reduce the detection limits of biologically active analytes. A topical trend in capillary electrophoresis required in clinical practice, viz., the design of microfluidic systems, is discussed.

AB - © 2015 Russian Academy of Sciences and Turpion Ltd.The review deals with modern analytical approaches used in capillary electrophoresis for solving medical and biological problems: search for biomarkers of various diseases and rapid diagnosis based on characteristic profiles of biologically active compounds by capillary electrophoresis with mass spectrometric detection; monitoring of the residual drugs in biological fluids for evaluating the efficiency of drug therapy; testing of the enantiomeric purity of pharmaceutical products; the use of novel materials as components of stationary and pseudo-stationary phases in capillary electrophoresis and capillary electrochromatography to increase the selectivity of separation of components of complex matrices; and identification of various on-line preconcentration techniques to reduce the detection limits of biologically active analytes. A topical trend in capillary electrophoresis required in clinical practice, viz., the design of microfluidic systems, is discussed.

U2 - 10.1070/RCR4492

DO - 10.1070/RCR4492

M3 - Literature review

VL - 84

SP - 860

EP - 874

JO - Russian Chemical Reviews

JF - Russian Chemical Reviews

SN - 0036-021X

IS - 8

ER -

ID: 4004144