TY - JOUR

T1 - Automated deep eutectic solvent-based chromatomembrane microextraction: Separation and preconcentration of bisphenols from aqueous samples

AU - Shishov, A.

AU - Israelyan, D.

AU - Bulatov, A.

N1 - Export Date: 21 March 2024 CODEN: SPUTF Адрес для корреспонденции: Shishov, A.; Department of Analytical Chemistry, SPbSU, SPbU, 7/9 Universitetskaya nab., Russian Federation; эл. почта: a.y.shishov@spbu.ru Сведения о финансировании: Saint Petersburg State University, SPbU Сведения о финансировании: Russian Science Foundation, RSF, 22-73-10039 Текст о финансировании 1: Andrey Shishov gratefully acknowledges financial support of Russian Science Foundation (research projects No. 22-73-10039). Scientific research was performed using the equipment of the Research Park of St. Petersburg State University (Chemical Analysis and Materials Research Centre and Center for Research of Extreme States of Materials and Structures). Dedicated to the 300-th anniversary of Saint Petersburg State University. Текст о финансировании 2: Andrey Shishov gratefully acknowledges financial support of Russian Science Foundation (research projects No. 22-73-10039). Scientific research was performed using the equipment of the Research Park of St. Petersburg State University (Chemical Analysis and Materials Research Centre and Center for Research of Extreme States of Materials and Structures). Dedicated to the 300-th anniversary of Saint Petersburg State University .

PY - 2024/6/1

Y1 - 2024/6/1

N2 - In this study, an automated, green deep eutectic solvent-based chromatomembrane microextraction approach was developed for separation and preconcentration of organic pollutants from aqueous samples. A design of a chromatomembrane cell (a polytetrafluoroethylene block coated with hydrophobic membranes) ensured automated and continuous liquid–liquid microextraction in deep eutectic solvent and separation of extract phase from aqueous sample phase. It was shown that hydrophobic deep eutectic solvents based on terpene and fatty alcohol/acid can be retained in micropores of the block and acted as a stationary phase in chromatomembrane process. Meanwhile, macropores in the block provide the penetration of aqueous phase and its movement through the block containing the liquid stationary phase (deep eutectic solvent). The large surface contact between the aqueous and deep eutectic solvent phases obtained in the block allowed to achieve on line separation (extraction recovery > 95 %) and preconcentration (enrichment factor > 10). The proposed approach was applied to microextraction of organic pollutants (bisphenols A, E and BP) from aqueous samples followed by their determination by high performance liquid chromatography with fluorometric detection. Under optimal conditions, the limits of detection for bisphenols were 0.03 µg/L. The developed microextraction sample preparation procedure is automated and compatible with liquid chromatography. © 2024 Elsevier B.V.

AB - In this study, an automated, green deep eutectic solvent-based chromatomembrane microextraction approach was developed for separation and preconcentration of organic pollutants from aqueous samples. A design of a chromatomembrane cell (a polytetrafluoroethylene block coated with hydrophobic membranes) ensured automated and continuous liquid–liquid microextraction in deep eutectic solvent and separation of extract phase from aqueous sample phase. It was shown that hydrophobic deep eutectic solvents based on terpene and fatty alcohol/acid can be retained in micropores of the block and acted as a stationary phase in chromatomembrane process. Meanwhile, macropores in the block provide the penetration of aqueous phase and its movement through the block containing the liquid stationary phase (deep eutectic solvent). The large surface contact between the aqueous and deep eutectic solvent phases obtained in the block allowed to achieve on line separation (extraction recovery > 95 %) and preconcentration (enrichment factor > 10). The proposed approach was applied to microextraction of organic pollutants (bisphenols A, E and BP) from aqueous samples followed by their determination by high performance liquid chromatography with fluorometric detection. Under optimal conditions, the limits of detection for bisphenols were 0.03 µg/L. The developed microextraction sample preparation procedure is automated and compatible with liquid chromatography. © 2024 Elsevier B.V.

KW - Aqueous samples

KW - Automated liquid–liquid microextraction

KW - Bisphenols

KW - Chromatomembrane method

KW - Deep eutectic solvent

KW - Liquid chromatography

KW - Membrane-based methods

UR - https://www.mendeley.com/catalogue/64df8688-e4a9-375c-9d39-62fece4b5b70/

U2 - 10.1016/j.seppur.2024.126480

DO - 10.1016/j.seppur.2024.126480

M3 - статья

VL - 338

JO - Separation and Purification Technology

JF - Separation and Purification Technology

SN - 1383-5866

ER -