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Attention-deicit hyperactivity disorder. / Sotnikova, Tatyana D.; Gainetdinov, Raul R.

Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders. Cambridge University Press, 2014. p. 164-172.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Harvard

Sotnikova, TD & Gainetdinov, RR 2014, Attention-deicit hyperactivity disorder. in Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders. Cambridge University Press, pp. 164-172. https://doi.org/10.1007/CBO9781107360556

APA

Sotnikova, T. D., & Gainetdinov, R. R. (2014). Attention-deicit hyperactivity disorder. In Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders (pp. 164-172). Cambridge University Press. https://doi.org/10.1007/CBO9781107360556

Vancouver

Sotnikova TD, Gainetdinov RR. Attention-deicit hyperactivity disorder. In Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders. Cambridge University Press. 2014. p. 164-172 https://doi.org/10.1007/CBO9781107360556

Author

Sotnikova, Tatyana D. ; Gainetdinov, Raul R. / Attention-deicit hyperactivity disorder. Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders. Cambridge University Press, 2014. pp. 164-172

BibTeX

@inbook{75b77efb84d64901ad496f010083acde,
title = "Attention-deicit hyperactivity disorder",
abstract = "Attention-deicit hyperactivity disorder (ADHD) is one of the most common developmental disorders afecting a signiicant proportion of children (5 to 7%) (Willcutt, 2012) and is primarily characterized by impulsivity, hyperactivity, and inattention. Attention-deicit hyperactivity disorder remains a disorder with unknown etiology however, multiple clinical observations have indicated that ADHD pathogenesis has a strong genetic inluence. In fact, the genetic component in ADHD development exceeds that of well-established disorders with signiicant genetic contributions such as depression and anxiety disorders (Barkley, 1997 Mill, 2007 Russell, 2007 Swanson et al., 2007). hus, it might be expected that ADHD could be modeled in animals by targeting speciic genes believed to be involved in this disorder. Certainly, a note of caution should be made when attempting to use rodents to recapitulate a human brain disorder with a complex set of cognitive and psychological manifestations. The mouse brain circuitry organization, particularly in the frontal cortex, is not as developed as in humans. Notably, as well, key behavioral characteristics of ADHD such as attention and impulsivity can be investigated in mice only partially due to technical diiculties.",
author = "Sotnikova, {Tatyana D.} and Gainetdinov, {Raul R.}",
year = "2014",
month = jan,
day = "1",
doi = "10.1007/CBO9781107360556",
language = "English",
isbn = "9781107044456",
pages = "164--172",
booktitle = "Behavioral Genetics of the Mouse Volume II",
publisher = "Cambridge University Press",
address = "United Kingdom",

}

RIS

TY - CHAP

T1 - Attention-deicit hyperactivity disorder

AU - Sotnikova, Tatyana D.

AU - Gainetdinov, Raul R.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Attention-deicit hyperactivity disorder (ADHD) is one of the most common developmental disorders afecting a signiicant proportion of children (5 to 7%) (Willcutt, 2012) and is primarily characterized by impulsivity, hyperactivity, and inattention. Attention-deicit hyperactivity disorder remains a disorder with unknown etiology however, multiple clinical observations have indicated that ADHD pathogenesis has a strong genetic inluence. In fact, the genetic component in ADHD development exceeds that of well-established disorders with signiicant genetic contributions such as depression and anxiety disorders (Barkley, 1997 Mill, 2007 Russell, 2007 Swanson et al., 2007). hus, it might be expected that ADHD could be modeled in animals by targeting speciic genes believed to be involved in this disorder. Certainly, a note of caution should be made when attempting to use rodents to recapitulate a human brain disorder with a complex set of cognitive and psychological manifestations. The mouse brain circuitry organization, particularly in the frontal cortex, is not as developed as in humans. Notably, as well, key behavioral characteristics of ADHD such as attention and impulsivity can be investigated in mice only partially due to technical diiculties.

AB - Attention-deicit hyperactivity disorder (ADHD) is one of the most common developmental disorders afecting a signiicant proportion of children (5 to 7%) (Willcutt, 2012) and is primarily characterized by impulsivity, hyperactivity, and inattention. Attention-deicit hyperactivity disorder remains a disorder with unknown etiology however, multiple clinical observations have indicated that ADHD pathogenesis has a strong genetic inluence. In fact, the genetic component in ADHD development exceeds that of well-established disorders with signiicant genetic contributions such as depression and anxiety disorders (Barkley, 1997 Mill, 2007 Russell, 2007 Swanson et al., 2007). hus, it might be expected that ADHD could be modeled in animals by targeting speciic genes believed to be involved in this disorder. Certainly, a note of caution should be made when attempting to use rodents to recapitulate a human brain disorder with a complex set of cognitive and psychological manifestations. The mouse brain circuitry organization, particularly in the frontal cortex, is not as developed as in humans. Notably, as well, key behavioral characteristics of ADHD such as attention and impulsivity can be investigated in mice only partially due to technical diiculties.

UR - http://www.scopus.com/inward/record.url?scp=84953269054&partnerID=8YFLogxK

U2 - 10.1007/CBO9781107360556

DO - 10.1007/CBO9781107360556

M3 - Chapter

AN - SCOPUS:84953269054

SN - 9781107044456

SP - 164

EP - 172

BT - Behavioral Genetics of the Mouse Volume II

PB - Cambridge University Press

ER -

ID: 36302061