• I. V. Kiseleva
  • A. Yu Yegorov
  • G. I. Alexandrova
  • O. A. Axyonov
  • Z. A. Osipova
  • L. P. Mayorova
  • A. I. Klimov

Influenza virus suppressed tumor growth after injection to tumor zone In a dose of 7-8 Ig EID50, as was shown for two continuous mouse tumor cell strains, Ehrlich's carcinoma and L-1210 lymphoma. Influenza virus strains differed by their antitumor activity which correlated with their interferonogenic activity. Antitumor activity of influenza virus depended on the site of application, dose of the virus, and interferonogenic activity. Virus therapy of tumors stimulated specific cytotoxic activity towards tumor antigens.

Original languageEnglish
Pages (from-to)29-32
Number of pages4
JournalVoprosy Virusologii
Volume44
Issue number1
StatePublished - 1999

    Scopus subject areas

  • Virology
  • Infectious Diseases

    Research areas

  • Cold-adapted strains, Influenza virus, Interferon, Tumor growth

ID: 75085367