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@article{4f5c3040c0da4f43b7c175df092b1b2e,
title = "An efficient synthesis of substituted spiro[isoxazolopyrroloisoquinolines] via diastereoselective N-acyliminium ion cyclization",
abstract = "{\textcopyright} 2015 Elsevier Ltd.A simple and efficient strategy is reported for the synthesis of spiro-fused pyrrolo[2,1-a]isoquinoline ring systems. The spiro[isoxazolopyrroloisoquinolines] are readily prepared via diastereoselective N-acyliminium ion cyclization of 6-hydroxy-7-(2-arylethyl)-1-oxa-2,7-diazaspiro[4.4]non-2-en-8-ones derived from the corresponding spirocyclic dihydroisoxazoles.",
author = "Ledovskaya, {Maria S.} and Stepakov, {Alexander V.} and Molchanov, {Alexander P.} and Kostikov, {Rafael R.}",
year = "2015",
doi = "10.1016/j.tet.2015.08.007",
language = "English",
volume = "71",
pages = "7562--7566",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier",
number = "40",

}

RIS

TY - JOUR

T1 - An efficient synthesis of substituted spiro[isoxazolopyrroloisoquinolines] via diastereoselective N-acyliminium ion cyclization

AU - Ledovskaya, Maria S.

AU - Stepakov, Alexander V.

AU - Molchanov, Alexander P.

AU - Kostikov, Rafael R.

PY - 2015

Y1 - 2015

N2 - © 2015 Elsevier Ltd.A simple and efficient strategy is reported for the synthesis of spiro-fused pyrrolo[2,1-a]isoquinoline ring systems. The spiro[isoxazolopyrroloisoquinolines] are readily prepared via diastereoselective N-acyliminium ion cyclization of 6-hydroxy-7-(2-arylethyl)-1-oxa-2,7-diazaspiro[4.4]non-2-en-8-ones derived from the corresponding spirocyclic dihydroisoxazoles.

AB - © 2015 Elsevier Ltd.A simple and efficient strategy is reported for the synthesis of spiro-fused pyrrolo[2,1-a]isoquinoline ring systems. The spiro[isoxazolopyrroloisoquinolines] are readily prepared via diastereoselective N-acyliminium ion cyclization of 6-hydroxy-7-(2-arylethyl)-1-oxa-2,7-diazaspiro[4.4]non-2-en-8-ones derived from the corresponding spirocyclic dihydroisoxazoles.

U2 - 10.1016/j.tet.2015.08.007

DO - 10.1016/j.tet.2015.08.007

M3 - Article

VL - 71

SP - 7562

EP - 7566

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 40

ER -

ID: 4004793