Research output: Contribution to journal › Article › peer-review
An efficient synthesis of substituted spiro[isoxazolopyrroloisoquinolines] via diastereoselective N-acyliminium ion cyclization. / Ledovskaya, Maria S.; Stepakov, Alexander V.; Molchanov, Alexander P.; Kostikov, Rafael R.
In: Tetrahedron, Vol. 71, No. 40, 2015, p. 7562-7566.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - An efficient synthesis of substituted spiro[isoxazolopyrroloisoquinolines] via diastereoselective N-acyliminium ion cyclization
AU - Ledovskaya, Maria S.
AU - Stepakov, Alexander V.
AU - Molchanov, Alexander P.
AU - Kostikov, Rafael R.
PY - 2015
Y1 - 2015
N2 - © 2015 Elsevier Ltd.A simple and efficient strategy is reported for the synthesis of spiro-fused pyrrolo[2,1-a]isoquinoline ring systems. The spiro[isoxazolopyrroloisoquinolines] are readily prepared via diastereoselective N-acyliminium ion cyclization of 6-hydroxy-7-(2-arylethyl)-1-oxa-2,7-diazaspiro[4.4]non-2-en-8-ones derived from the corresponding spirocyclic dihydroisoxazoles.
AB - © 2015 Elsevier Ltd.A simple and efficient strategy is reported for the synthesis of spiro-fused pyrrolo[2,1-a]isoquinoline ring systems. The spiro[isoxazolopyrroloisoquinolines] are readily prepared via diastereoselective N-acyliminium ion cyclization of 6-hydroxy-7-(2-arylethyl)-1-oxa-2,7-diazaspiro[4.4]non-2-en-8-ones derived from the corresponding spirocyclic dihydroisoxazoles.
U2 - 10.1016/j.tet.2015.08.007
DO - 10.1016/j.tet.2015.08.007
M3 - Article
VL - 71
SP - 7562
EP - 7566
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 40
ER -
ID: 4004793