Standard

A role of endophilin A in the synaptic vesicle liquid phase. / Sopova, E. ; Korenkova, O. ; Onochin, K. ; Brodin, L.; Shupliakov, O. .

In: European Neuropsychopharmacology, Vol. 53 , No. Supplement 1, P.0557 , 12.2021, p. S409-S410.

Research output: Contribution to journal › Conference article › peer-review

Harvard

Sopova, E, Korenkova, O, Onochin, K, Brodin, L & Shupliakov, O 2021, 'A role of endophilin A in the synaptic vesicle liquid phase', European Neuropsychopharmacology, vol. 53 , no. Supplement 1, P.0557 , pp. S409-S410. https://doi.org/10.1016/j.euroneuro.2021.10.527

APA

Sopova, E., Korenkova, O., Onochin, K., Brodin, L., & Shupliakov, O. (2021). A role of endophilin A in the synaptic vesicle liquid phase. European Neuropsychopharmacology, 53 (Supplement 1), S409-S410. [P.0557 ]. https://doi.org/10.1016/j.euroneuro.2021.10.527

Vancouver

Sopova E, Korenkova O, Onochin K, Brodin L, Shupliakov O. A role of endophilin A in the synaptic vesicle liquid phase. European Neuropsychopharmacology. 2021 Dec;53 (Supplement 1):S409-S410. P.0557 . https://doi.org/10.1016/j.euroneuro.2021.10.527

Author

Sopova, E. ; Korenkova, O. ; Onochin, K. ; Brodin, L. ; Shupliakov, O. . / A role of endophilin A in the synaptic vesicle liquid phase. In: European Neuropsychopharmacology. 2021 ; Vol. 53 , No. Supplement 1. pp. S409-S410.

BibTeX

@article{329c9c5d57e9479fbff499bbd8dc41bb,
title = "A role of endophilin A in the synaptic vesicle liquid phase",
abstract = "Protein liquid phase transition into a solid state has been proposed as a mechanism for the onset of pathological protein aggregate formation in neurodegenerative diseases, such as Alzheimer{\textquoteright}s and Parkinson{\textquoteright}s diseases. The synaptic vesicle (SV) cluster is one of the compartments that is proposed to be organized by liquid-liquid phase separation (LLPS), in which the phosphoprotein synapsin plays the key role. To determine possible involvement of the synaptic vesicle liquid phase in pathological transformations it is important to know how this phase is functionally regulated. In addition to synapsin, SV clusters contain an array of proteins with SH3 domains, some of which interact with synapsin. It the current study we investigated the localisation and regulation of the SH3 domain-containing protein endophilin A in the organization of the synaptic vesicle liquid phase in identified inhibitory and excitatory synapses. ",
author = "E. Sopova and O. Korenkova and K. Onochin and L. Brodin and O. Shupliakov",
year = "2021",
month = dec,
doi = "10.1016/j.euroneuro.2021.10.527",
language = "English",
volume = "53 ",
pages = "S409--S410",
journal = "European Neuropsychopharmacology",
issn = "0924-977X",
publisher = "Elsevier",
number = "Supplement 1",
note = "null ; Conference date: 02-10-2021 Through 05-10-2021",

}

RIS

TY - JOUR

T1 - A role of endophilin A in the synaptic vesicle liquid phase

AU - Sopova, E.

AU - Korenkova, O.

AU - Onochin, K.

AU - Brodin, L.

AU - Shupliakov, O.

PY - 2021/12

Y1 - 2021/12

N2 - Protein liquid phase transition into a solid state has been proposed as a mechanism for the onset of pathological protein aggregate formation in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases. The synaptic vesicle (SV) cluster is one of the compartments that is proposed to be organized by liquid-liquid phase separation (LLPS), in which the phosphoprotein synapsin plays the key role. To determine possible involvement of the synaptic vesicle liquid phase in pathological transformations it is important to know how this phase is functionally regulated. In addition to synapsin, SV clusters contain an array of proteins with SH3 domains, some of which interact with synapsin. It the current study we investigated the localisation and regulation of the SH3 domain-containing protein endophilin A in the organization of the synaptic vesicle liquid phase in identified inhibitory and excitatory synapses.

AB - Protein liquid phase transition into a solid state has been proposed as a mechanism for the onset of pathological protein aggregate formation in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases. The synaptic vesicle (SV) cluster is one of the compartments that is proposed to be organized by liquid-liquid phase separation (LLPS), in which the phosphoprotein synapsin plays the key role. To determine possible involvement of the synaptic vesicle liquid phase in pathological transformations it is important to know how this phase is functionally regulated. In addition to synapsin, SV clusters contain an array of proteins with SH3 domains, some of which interact with synapsin. It the current study we investigated the localisation and regulation of the SH3 domain-containing protein endophilin A in the organization of the synaptic vesicle liquid phase in identified inhibitory and excitatory synapses.

UR - https://www.sciencedirect.com/science/article/abs/pii/S0924977X21012980#!

U2 - 10.1016/j.euroneuro.2021.10.527

DO - 10.1016/j.euroneuro.2021.10.527

M3 - Conference article

VL - 53

SP - S409-S410

JO - European Neuropsychopharmacology

JF - European Neuropsychopharmacology

SN - 0924-977X

IS - Supplement 1

M1 - P.0557

Y2 - 2 October 2021 through 5 October 2021

ER -

ID: 83997338