DOI

A straightforward access to novel spiro[benzofuran-2,3'-pyrrolidine]-2',5'-diones based on the Rh2(esp)2-catalyzed insertion of carbenes derived from diazo arylidene succinimides (DAS) into the O–H bond of phenols is described. The initial adducts underwent a thermally promoted Claisen rearrangement followed by DABCO-catalyzed intramolecular 5-exo-trig oxa-Michael addition.
Original languageEnglish
Pages (from-to)1649-1655
JournalBeilstein Journal of Organic Chemistry
Issue number18
DOIs
StatePublished - 2022

    Research areas

  • CLAISEN REARRANGEMENT, diazo arylidene succinimides, intramolecular oxa-Michael addition, rhodium(II) carbene O–H insertion, spirocycles

ID: 101522044