Research output: Contribution to journal › Article › peer-review
A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides. / Zhmurov, Petr A.; Ushakov, Pavel Yu; Novikov, Roman A.; Sukhorukov, Alexey Yu; Ioffe, Sema L.
In: Synlett, Vol. 29, No. 14, 01.01.2018, p. 1871-1874.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides
AU - Zhmurov, Petr A.
AU - Ushakov, Pavel Yu
AU - Novikov, Roman A.
AU - Sukhorukov, Alexey Yu
AU - Ioffe, Sema L.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - A novel strategy for the synthesis of stereochemically defined 3,4,5-trisubstituted 2-pyrrolidones was developed. The suggested approach involves reductive domino-type recyclization of 3-aminomethyl-substituted isoxazolines as a key stage. The latter are prepared via α-C-H functionalization of readily available isoxazoline-N-oxides.
AB - A novel strategy for the synthesis of stereochemically defined 3,4,5-trisubstituted 2-pyrrolidones was developed. The suggested approach involves reductive domino-type recyclization of 3-aminomethyl-substituted isoxazolines as a key stage. The latter are prepared via α-C-H functionalization of readily available isoxazoline-N-oxides.
KW - 2-pyrrolidones
KW - azides
KW - C-H functionalization
KW - isoxazolines
KW - reduction
UR - http://www.scopus.com/inward/record.url?scp=85051941775&partnerID=8YFLogxK
U2 - 10.1055/s-0037-1610213
DO - 10.1055/s-0037-1610213
M3 - Article
AN - SCOPUS:85051941775
VL - 29
SP - 1871
EP - 1874
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 14
ER -
ID: 51899879