Research output: Contribution to journal › Article › peer-review
A novel bis-triazole scaffold accessed via two tandem [3 + 2] cycloaddition events including an uncatalyzed, room temperature azide–alkyne click reaction. / Malkova, Ksenia ; Bubyrev, Andrey ; Krivovicheva, Vasilisa ; Dar’in, Dmitry ; Bunev, Alexander ; Krasavin, Mikhail .
In: Beilstein Journal of Organic Chemistry, No. 18, 12.2022, p. 1636-1641.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - A novel bis-triazole scaffold accessed via two tandem [3 + 2] cycloaddition events including an uncatalyzed, room temperature azide–alkyne click reaction
AU - Malkova, Ksenia
AU - Bubyrev, Andrey
AU - Krivovicheva, Vasilisa
AU - Dar’in, Dmitry
AU - Bunev, Alexander
AU - Krasavin, Mikhail
PY - 2022/12
Y1 - 2022/12
N2 - The previously described α-acetyl-α-diazomethanesulfonamide was employed in a three-component reaction with azide-containing benzaldehydes and propargylamines. Besides the initial formation of the triazole core, the reaction proceeded further, in uncatalyzed fashion at room temperature and yielded, after intramolecular azide–alkyne click reaction novel, structurally intriguing bistriazoles.
AB - The previously described α-acetyl-α-diazomethanesulfonamide was employed in a three-component reaction with azide-containing benzaldehydes and propargylamines. Besides the initial formation of the triazole core, the reaction proceeded further, in uncatalyzed fashion at room temperature and yielded, after intramolecular azide–alkyne click reaction novel, structurally intriguing bistriazoles.
KW - α-acetyl-α-diazomethane sulfonamide
KW - intramolecular click reaction
KW - uncatalyzed
KW - room temperature
KW - 1,2,3-triazoles
U2 - https://doi.org/10.3762/bjoc.18.175
DO - https://doi.org/10.3762/bjoc.18.175
M3 - Article
SP - 1636
EP - 1641
JO - Beilstein Journal of Organic Chemistry
JF - Beilstein Journal of Organic Chemistry
SN - 1860-5397
IS - 18
ER -
ID: 101521916