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A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins. / Baranova, M.; Romanenko, M.; Savina, I.; Pilipenko, E.; Belozerova, O.; Terekhov, S.; Nizhnikov, A.; Antonets, K.; Smirnov, I.

In: Biological Communications, Vol. 69, No. 2, 10.10.2024, p. 111-116.

Research output: Contribution to journal › Article › peer-review

Harvard

Baranova, M, Romanenko, M, Savina, I, Pilipenko, E, Belozerova, O, Terekhov, S, Nizhnikov, A, Antonets, K & Smirnov, I 2024, 'A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins', Biological Communications, vol. 69, no. 2, pp. 111-116. https://doi.org/10.21638/spbu03.2024.206

APA

Baranova, M., Romanenko, M., Savina, I., Pilipenko, E., Belozerova, O., Terekhov, S., Nizhnikov, A., Antonets, K., & Smirnov, I. (2024). A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins. Biological Communications, 69(2), 111-116. https://doi.org/10.21638/spbu03.2024.206

Vancouver

Baranova M, Romanenko M, Savina I, Pilipenko E, Belozerova O, Terekhov S et al. A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins. Biological Communications. 2024 Oct 10;69(2):111-116. https://doi.org/10.21638/spbu03.2024.206

Author

Baranova, M. ; Romanenko, M. ; Savina, I. ; Pilipenko, E. ; Belozerova, O. ; Terekhov, S. ; Nizhnikov, A. ; Antonets, K. ; Smirnov, I. / A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins. In: Biological Communications. 2024 ; Vol. 69, No. 2. pp. 111-116.

BibTeX

@article{7c2c8146801d4fbd9342c0993c7b9b60,
title = "A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins",
abstract = "Soil is a classical source of beneficial microorganisms. Soil microbiomes provided the overwhelming majority of antibiotic-producing strains, biocontrol agents, probiotics, and plant-protecting bacteria. The functionality of strains isolated from various soil samples is predetermined by the biosynthetic potential encoded in their genomes. Here, we describe a novel Peribacillus simplex d27.3 strain isolated from the soil sample of a pine forest in the Republic of Dagestan, Russia. P. simplex d27.3 displayed antibiotic activity against gram-positive bacteria and fungi while being inactive against the model hypersensitive gram-negative strain E. coli ΔlptD. Metabolomic analysis revealed that antimicrobial activity was partially mediated by the fengycin lipopetides (C-16 fengycin A, C-17 fengycin A, and C-16 fengycin B). In addition, the P. simplex d27.3 strain was found to produce other hydrophilic and more hydrophobic antimicrobials yet to be described. Thus, the P. simplex d27.3 strain is a producer of useful antimicrobial compounds with a high potential for application in biotechnology and agriculture. Copyright: {\textcopyright} 2024 Baranova et al.",
keywords = "antibiotics, fengycins, Peribacillus simplex, soil microbiome",
author = "M. Baranova and M. Romanenko and I. Savina and E. Pilipenko and O. Belozerova and S. Terekhov and A. Nizhnikov and K. Antonets and I. Smirnov",
note = "Export Date: 10 November 2024 Сведения о финансировании: Russian Science Foundation, RSF, 19-14-00331 Сведения о финансировании: Russian Science Foundation, RSF Текст о финансировании 1: The research was funded by the Russian Science Foundation grant no. 19-14-00331. The authors acknowledge the Core Centrum \u201CGenomic Technologies, Proteomics and Cell Biology\u201D (All-Russia Research Institute of Agricultural Microbiology) and Center for Molecular and Cell Technologies (Research Park, St. Petersburg State University) for the equipment provided for use in this work.",
year = "2024",
month = oct,
day = "10",
doi = "10.21638/spbu03.2024.206",
language = "Английский",
volume = "69",
pages = "111--116",
journal = "Biological Communications",
issn = "2542-2154",
publisher = "Издательство Санкт-Петербургского университета",
number = "2",

}

RIS

TY - JOUR

T1 - A new Peribacillus simplex d27.3 strain mediates antimicrobial activity through a combination of secondary metabolites, including fengycins

AU - Baranova, M.

AU - Romanenko, M.

AU - Savina, I.

AU - Pilipenko, E.

AU - Belozerova, O.

AU - Terekhov, S.

AU - Nizhnikov, A.

AU - Antonets, K.

AU - Smirnov, I.

N1 - Export Date: 10 November 2024 Сведения о финансировании: Russian Science Foundation, RSF, 19-14-00331 Сведения о финансировании: Russian Science Foundation, RSF Текст о финансировании 1: The research was funded by the Russian Science Foundation grant no. 19-14-00331. The authors acknowledge the Core Centrum \u201CGenomic Technologies, Proteomics and Cell Biology\u201D (All-Russia Research Institute of Agricultural Microbiology) and Center for Molecular and Cell Technologies (Research Park, St. Petersburg State University) for the equipment provided for use in this work.

PY - 2024/10/10

Y1 - 2024/10/10

N2 - Soil is a classical source of beneficial microorganisms. Soil microbiomes provided the overwhelming majority of antibiotic-producing strains, biocontrol agents, probiotics, and plant-protecting bacteria. The functionality of strains isolated from various soil samples is predetermined by the biosynthetic potential encoded in their genomes. Here, we describe a novel Peribacillus simplex d27.3 strain isolated from the soil sample of a pine forest in the Republic of Dagestan, Russia. P. simplex d27.3 displayed antibiotic activity against gram-positive bacteria and fungi while being inactive against the model hypersensitive gram-negative strain E. coli ΔlptD. Metabolomic analysis revealed that antimicrobial activity was partially mediated by the fengycin lipopetides (C-16 fengycin A, C-17 fengycin A, and C-16 fengycin B). In addition, the P. simplex d27.3 strain was found to produce other hydrophilic and more hydrophobic antimicrobials yet to be described. Thus, the P. simplex d27.3 strain is a producer of useful antimicrobial compounds with a high potential for application in biotechnology and agriculture. Copyright: © 2024 Baranova et al.

AB - Soil is a classical source of beneficial microorganisms. Soil microbiomes provided the overwhelming majority of antibiotic-producing strains, biocontrol agents, probiotics, and plant-protecting bacteria. The functionality of strains isolated from various soil samples is predetermined by the biosynthetic potential encoded in their genomes. Here, we describe a novel Peribacillus simplex d27.3 strain isolated from the soil sample of a pine forest in the Republic of Dagestan, Russia. P. simplex d27.3 displayed antibiotic activity against gram-positive bacteria and fungi while being inactive against the model hypersensitive gram-negative strain E. coli ΔlptD. Metabolomic analysis revealed that antimicrobial activity was partially mediated by the fengycin lipopetides (C-16 fengycin A, C-17 fengycin A, and C-16 fengycin B). In addition, the P. simplex d27.3 strain was found to produce other hydrophilic and more hydrophobic antimicrobials yet to be described. Thus, the P. simplex d27.3 strain is a producer of useful antimicrobial compounds with a high potential for application in biotechnology and agriculture. Copyright: © 2024 Baranova et al.

KW - antibiotics

KW - fengycins

KW - Peribacillus simplex

KW - soil microbiome

UR - https://www.mendeley.com/catalogue/c1ba9348-bb4f-3abc-a1a2-0d646c63a359/

U2 - 10.21638/spbu03.2024.206

DO - 10.21638/spbu03.2024.206

M3 - статья

VL - 69

SP - 111

EP - 116

JO - Biological Communications

JF - Biological Communications

SN - 2542-2154

IS - 2

ER -

ID: 127213332