Due to the need to reindustrialize the domestic industry at the post-industrial stage of development, it has become necessary to implement megaprojects aiming at the qualitative makeover of the national economy. The “reindustrialization” problem in the Russian Federation is aggravated by the world economic & political crisis. The purpose of this research is a comparative analysis of risk management and developing a model of industrial megaproject risk management. The research has resulted in two megaproject risk management models: a fragmentary model and a comprehensive one. A risk mitigation potential analysis for ongoing megaprojects has been performed confirming the efficiency of use of the comprehensive megaproject risk management model. The suggested comprehensive risk management model allows taking into consideration the main distinctive feature of modern megaprojects, i.e. multiplicity of management entities operating on the basis of the partnership principle.