Research output: Contribution to journal › Review article › peer-review
A building block approach to monofluorinated organic compounds. / Konev, Alexander S.; Khlebnikov, Alexander F.
In: Collection of Czechoslovak Chemical Communications, Vol. 73, No. 12, 01.12.2008, p. 1553-1611.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - A building block approach to monofluorinated organic compounds
AU - Konev, Alexander S.
AU - Khlebnikov, Alexander F.
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Building blocks for the synthesis of monofluorinated organic compounds are reviewed. The synthetic potential of polyhalomethanes, sulfur- and phosphorus-containing building blocks, difluoroethene, polyhaloethanes, fluoroacetic acid derivatives, and other compounds are described. Pericyclic reactions involving fluorinated compounds and application of the methodology of building blocks to the synthesis of monofluorinated pharmaceuticals and analogs of natural compounds are considered. The review with 317 references covers mainly the literature from 1996 through 2007.
AB - Building blocks for the synthesis of monofluorinated organic compounds are reviewed. The synthetic potential of polyhalomethanes, sulfur- and phosphorus-containing building blocks, difluoroethene, polyhaloethanes, fluoroacetic acid derivatives, and other compounds are described. Pericyclic reactions involving fluorinated compounds and application of the methodology of building blocks to the synthesis of monofluorinated pharmaceuticals and analogs of natural compounds are considered. The review with 317 references covers mainly the literature from 1996 through 2007.
KW - Fluorinated building blocks
KW - Fluorinated organic compounds
KW - Synthesis design
UR - http://www.scopus.com/inward/record.url?scp=59849116724&partnerID=8YFLogxK
U2 - 10.1135/cccc20081553
DO - 10.1135/cccc20081553
M3 - Review article
AN - SCOPUS:59849116724
VL - 73
SP - 1553
EP - 1611
JO - ChemPlusChem
JF - ChemPlusChem
SN - 2192-6506
IS - 12
ER -
ID: 28187737