47Glioblastoma gene expression profile diagnostics by the artificial neural networks. / Mekler, A.A.; Knyazeva, I.; Schwartz, D.R.; Kuperin, Y.A.; Dmitrenko, V.V.; Rymar, V.I.; Kavsan, V.M.
In: Optical Memory and Neural Networks (Information Optics), Vol. 19, No. 2, 2010, p. 181-186.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - 47Glioblastoma gene expression profile diagnostics by the artificial neural networks
AU - Mekler, A.A.
AU - Knyazeva, I.
AU - Schwartz, D.R.
AU - Kuperin, Y.A.
AU - Dmitrenko, V.V.
AU - Rymar, V.I.
AU - Kavsan, V.M.
PY - 2010
Y1 - 2010
N2 - Two artificial neural networks of different types were applied to gene expression profiles in glioblastoma, the most aggressive human brain tumor, and in normal brain tissue. The results of gene expression profiles classification are presented. First method, self organizing maps, gave good discrimination of profiles on the trained map. Another ANN, perceptron, showed a good result of classificatio - more then 95% of the test data set were successfully classified. Due to high correlations between some gene expression values one can suppose, that number of genes necessary for successful classification may be reduced. © 2010 Allerton Press, Inc.
AB - Two artificial neural networks of different types were applied to gene expression profiles in glioblastoma, the most aggressive human brain tumor, and in normal brain tissue. The results of gene expression profiles classification are presented. First method, self organizing maps, gave good discrimination of profiles on the trained map. Another ANN, perceptron, showed a good result of classificatio - more then 95% of the test data set were successfully classified. Due to high correlations between some gene expression values one can suppose, that number of genes necessary for successful classification may be reduced. © 2010 Allerton Press, Inc.
U2 - 10.3103/S1060992X10020098
DO - 10.3103/S1060992X10020098
M3 - Article
VL - 19
SP - 181
EP - 186
JO - Optical Memory and Neural Networks (Information Optics)
JF - Optical Memory and Neural Networks (Information Optics)
SN - 1060-992X
IS - 2
ER -
ID: 8183303