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2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+. / Gorshkov, N. I.; Lumpov, A. A.; Miroslavov, A. E.; Suglobov, D. N.

In: Radiochemistry, Vol. 47, No. 1, 01.2005, p. 45-49.

Research output: Contribution to journal › Article › peer-review

Harvard

Gorshkov, NI, Lumpov, AA, Miroslavov, AE & Suglobov, DN 2005, '2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+', Radiochemistry, vol. 47, no. 1, pp. 45-49. https://doi.org/10.1007/s11137-005-0045-2

APA

Gorshkov, N. I., Lumpov, A. A., Miroslavov, A. E., & Suglobov, D. N. (2005). 2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+. Radiochemistry, 47(1), 45-49. https://doi.org/10.1007/s11137-005-0045-2

Vancouver

Gorshkov NI, Lumpov AA, Miroslavov AE, Suglobov DN. 2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+. Radiochemistry. 2005 Jan;47(1):45-49. https://doi.org/10.1007/s11137-005-0045-2

Author

Gorshkov, N. I. ; Lumpov, A. A. ; Miroslavov, A. E. ; Suglobov, D. N. / 2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+. In: Radiochemistry. 2005 ; Vol. 47, No. 1. pp. 45-49.

BibTeX

@article{8f90953cf6c646e5ad1f63b64aadd456,
title = "2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+",
abstract = "Complexation of 99, 99m Tc(CO) 3 + organometallic fragment with 2 + 1 chelating systems was studied. HPLC analysis showed that the dithiocarbamate complexes of 99m Tc are stronger than their xanthate, acetylacetonate, and γ- methoxycarbonylmethylacetylacetonate analogs. To block the third vacancy in the technetium coordination sphere, we studied thiols, thioethers, primary and secondary amines, hydroxyl ion, imidazole, phosphines, and isocyanides. As determined by 99m Tc NMR spectroscopy, the mixed-ligand complexes Tc(CO)3(DTC)L (DTC is dithiocarbamate and L is isocyanide, imidazole, and phosphine) are the most stable to the histidine challenge reaction. HPLC analysis showed that, among these 2 + 1 systems, only the DTC-isonitrile system forms a single complex with 99m Tc(CO) 3 + . The minimal dithiocarbamate-isocyanide concentration providing complete binding of 99m Tc(CO) 3 + is 10-4 M.",
author = "Gorshkov, {N. I.} and Lumpov, {A. A.} and Miroslavov, {A. E.} and Suglobov, {D. N.}",
note = "Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
year = "2005",
month = jan,
doi = "10.1007/s11137-005-0045-2",
language = "English",
volume = "47",
pages = "45--49",
journal = "Radiochemistry",
issn = "1066-3622",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - 2 + 1 Chelating systems for binding organometallic fragment Tc(CO) 3+

AU - Gorshkov, N. I.

AU - Lumpov, A. A.

AU - Miroslavov, A. E.

AU - Suglobov, D. N.

N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2005/1

Y1 - 2005/1

N2 - Complexation of 99, 99m Tc(CO) 3 + organometallic fragment with 2 + 1 chelating systems was studied. HPLC analysis showed that the dithiocarbamate complexes of 99m Tc are stronger than their xanthate, acetylacetonate, and γ- methoxycarbonylmethylacetylacetonate analogs. To block the third vacancy in the technetium coordination sphere, we studied thiols, thioethers, primary and secondary amines, hydroxyl ion, imidazole, phosphines, and isocyanides. As determined by 99m Tc NMR spectroscopy, the mixed-ligand complexes Tc(CO)3(DTC)L (DTC is dithiocarbamate and L is isocyanide, imidazole, and phosphine) are the most stable to the histidine challenge reaction. HPLC analysis showed that, among these 2 + 1 systems, only the DTC-isonitrile system forms a single complex with 99m Tc(CO) 3 + . The minimal dithiocarbamate-isocyanide concentration providing complete binding of 99m Tc(CO) 3 + is 10-4 M.

AB - Complexation of 99, 99m Tc(CO) 3 + organometallic fragment with 2 + 1 chelating systems was studied. HPLC analysis showed that the dithiocarbamate complexes of 99m Tc are stronger than their xanthate, acetylacetonate, and γ- methoxycarbonylmethylacetylacetonate analogs. To block the third vacancy in the technetium coordination sphere, we studied thiols, thioethers, primary and secondary amines, hydroxyl ion, imidazole, phosphines, and isocyanides. As determined by 99m Tc NMR spectroscopy, the mixed-ligand complexes Tc(CO)3(DTC)L (DTC is dithiocarbamate and L is isocyanide, imidazole, and phosphine) are the most stable to the histidine challenge reaction. HPLC analysis showed that, among these 2 + 1 systems, only the DTC-isonitrile system forms a single complex with 99m Tc(CO) 3 + . The minimal dithiocarbamate-isocyanide concentration providing complete binding of 99m Tc(CO) 3 + is 10-4 M.

UR - http://www.scopus.com/inward/record.url?scp=21644459304&partnerID=8YFLogxK

U2 - 10.1007/s11137-005-0045-2

DO - 10.1007/s11137-005-0045-2

M3 - Article

AN - SCOPUS:21644459304

VL - 47

SP - 45

EP - 49

JO - Radiochemistry

JF - Radiochemistry

SN - 1066-3622

IS - 1

ER -

ID: 76836040