Research output: Contribution to journal › Article › peer-review
1,1′-Carbonyldiimidazole as a cyclodehydrating agent for the Castagnoli–Cushman reaction of dicarboxylic acids and imines. / Chupakhin, Evgeny G.; Bakulina, Olga Yu; Dar'in, Dmitry V.; Krasavin, Mikhail.
In: Mendeleev Communications , Vol. 29, No. 3, 01.05.2019, p. 292-293.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - 1,1′-Carbonyldiimidazole as a cyclodehydrating agent for the Castagnoli–Cushman reaction of dicarboxylic acids and imines
AU - Chupakhin, Evgeny G.
AU - Bakulina, Olga Yu
AU - Dar'in, Dmitry V.
AU - Krasavin, Mikhail
PY - 2019/5/1
Y1 - 2019/5/1
N2 - A novel protocol for the Castagnoli–Cushman reaction of dicarboxylic acids and imines comprises the use of 1,1′-carbonyldiimidazole as the cyclodehydrating agent to in situ produce the intermediate anhydrides. In contrast to previously developed procedure involving the use of acetic anhydride, the current protocol allows one to utilize substrates prone to acylation or acid-promoted transformations, which significantly broadens the reaction scope of lactams to be obtained.
AB - A novel protocol for the Castagnoli–Cushman reaction of dicarboxylic acids and imines comprises the use of 1,1′-carbonyldiimidazole as the cyclodehydrating agent to in situ produce the intermediate anhydrides. In contrast to previously developed procedure involving the use of acetic anhydride, the current protocol allows one to utilize substrates prone to acylation or acid-promoted transformations, which significantly broadens the reaction scope of lactams to be obtained.
KW - CYCLIC ANHYDRIDES
KW - PRODUCT SPACE
KW - DIVERSITY
UR - http://www.scopus.com/inward/record.url?scp=85066864141&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/11carbonyldiimidazole-cyclodehydrating-agent-castagnolicushman-reaction-dicarboxylic-acids-imines
U2 - 10.1016/j.mencom.2019.05.016
DO - 10.1016/j.mencom.2019.05.016
M3 - Article
AN - SCOPUS:85066864141
VL - 29
SP - 292
EP - 293
JO - Mendeleev Communications
JF - Mendeleev Communications
SN - 0959-9436
IS - 3
ER -
ID: 46259161