The article presents the results of a pilot study of stress resistance of men 20-30 years old with different levels of physical activity: professional athletes, engaged in physical culture, and not engaged in physical culture and sports. Used methods: questioning, stress testing, registration of physiological parameters. It was established that under the influence of stress factors, the dynamics of the electrical activity of the skin, heart rate, condition of vascular tone and blood vessels varies depending on the level of physical activity of men.