The article analyzes the reaction of the countries of the Arab region as well as the world powers to the next Palestinian-Israeli conflict that broke out on October 7, 2023. Regionally, most countries have taken a unified position – attributing responsibility for the attacks on Israel. Only a small number of countries in the region condemned all violence and called on the parties to the conflict to engage in peace talks. Harsh rhetoric was observed from one of the non-Arab actors in the region, Turkey, which openly declared its support for Hamas and condemned Israel’s actions. The escalating tone was also reflected in Iran’s official statements. The United States and its allies sided with Israel, declaring the right of Israelis to defend themselves. The position of Russia and China was to end the conflict as soon as possible, as well as the need to implement the two-state solution and the creation of an independent Palestinian state.