The analysis of two Edmund Spenser's epyllia “Prosopopoia” and “Muiopotmos” shows their semblance goes far beyond Greek words used in both titles. The poems exquisitely combine elements of age-old device of a bestiary with profound philosophical meditations on the volatility of human fates and fortunes. Spenser's indebtedness to Boetius's “De Consolatione philosophiae” is shown in “Prosopopoia”, the parable about the disorder of the times and craving for order and harmony, while “Muiopotmos” echoing some of the popular Renaissance ideas concerning the point of life is treated as a gorgeous mythological fantasy showing the dependence of a human fate on the person's ability to abstain from sensual indulgence and unrestrained search for pleasure.