The results of validation of Russian version of questionnaire “Scale of perceived stress-10” are presented. This version of questionnaire has high results of reliability and satisfactory results of validity. An exploratory factor analysis revealed good correspondence of forthcoming factorial structure of the questionnaire. The Scale of perceived stress-10 has high internal coordination. The results received by direct testing of constructive validity in general correspond to theoretically predicted ones. The received results give basis to suppose that Russian version of questionnaire “Scale of perceived stress-10” is reliable and valid instrument for national and cross cultural investigations. Refs 4. Fig. 1. Tables 6.