Up to now there is no an adult without a dental disease or a person who has never sought for medical help toa dental specialist. At the same time, in the routine dental practice there is no analysis of the each individual patient’s autoimmunity status. Neither genetic predisposition, no occupational hazards are taken into account, also it is often neglected the presence of autoimmune lesions of inner organs. Current data about factors in use in Dental Medicine, dental materials and medical products having an adjuvant or adjuvant-like nature that promote the development of autoimmune pathology in the structure of the autoimmunity mosaic are contained in this review (figure 1, bibliography: 66 refs).