Internet addiction (IA) is recognized as one of the common variants of non-chemical addictions which exerts significant negative social, medical and economic impacts on the person himself or herself, his or her family and society as a whole. Currently, studying the phenomenon of IA is conducted with the use of psychometric scales, which allow assessing the presence of IA or a high risk for its presence without making a clinical diagnosis. Objective: to identify possible associations between neurotransmitter systems gene polymorphisms and a risk for the development of IA of various degrees of severity, of individual symptoms and related problems of IA, as measured by the Chen Internet Addiction Scale (CIAS). The study was conducted using a gene panel (31 polymorphic loci in 22 genes), formed on the basis of a pathogenetic approach, with polymorphic variants of the genes that control the neurotransmitter systems (dopamine (DA), serotonin, GABA-glutamate), endogenous opioid system and neurotrophin signaling path