Роль ацил-грелина в белково-энергетической недостаточности у пациентов с хронической болезнью почек С5Д

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Роль ацил-грелина в белково-энергетической недостаточности у пациентов с хронической болезнью почек С5Д. / Yakovenko, A. A.; Lavrishcheva, Yu. V.; Rumyantsev, A. Sh.; Droganova, A. S.; Loginova, D. O.

In: Nephrology (Saint-Petersburg), Vol. 29, No. 2, 04.06.2025, p. 42-49.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{cdfc15b22bf14ce19c73f8be3b41f90b,

title = "Роль ацил-грелина в белково-энергетической недостаточности у пациентов с хронической болезнью почек С5Д",

abstract = "THE AIM OF THE STUDY. To clarify the role of acyl-ghrelin in the development of protein-energy wasting of haemodialysis patients (HD). PATIENTS AND METHODS. A total of 645 patients receiving treatment with programmatic bicarbonate HD for 8.4 ± 5.3 years, including 345 women and 300 men, the average age was 56.8 ± 12.8 years. Nutritional status was assessed using the method proposed by the International Society of Renal Nutrition and Metabolism (ISRNM). For the quantitative determination of acyl-ghrelin, the enzyme-linked immunosorbent assay kit “Active Ghrelin ELISA Kit” (highly sensitive method) from Sceti KK, Japan was used in this work. Reference values: 30-62 fmol/ml. RESULTS. The prevalence of protein-energy wasting (PEM) using the ISRNM method was 24.9% (160 patients). Reduced levels of acyl-ghrelin were detected in 352 patients (54.5%). The average acyl-ghrelin values in patients without signs of PEW were 50.2±10.3 fmol/ml, and in patients with PEW 24.9±9.2 fmol/ml (p",

keywords = "acyl-ghrelin, haemodialysis, protein-energy wasting",

author = "Yakovenko, {A. A.} and Lavrishcheva, {Yu. V.} and Rumyantsev, {A. Sh.} and Droganova, {A. S.} and Loginova, {D. O.}",

year = "2025",

month = jun,

day = "4",

doi = "10.36485/1561-6274-2025-29-2-42-49",

language = "русский",

volume = "29",

pages = "42--49",

journal = "Nephrology (Saint-Petersburg)",

issn = "1561-6274",

publisher = "Нефрология",

number = "2",

}

RIS

TY - JOUR

T1 - Роль ацил-грелина в белково-энергетической недостаточности у пациентов с хронической болезнью почек С5Д

AU - Yakovenko, A. A.

AU - Lavrishcheva, Yu. V.

AU - Rumyantsev, A. Sh.

AU - Droganova, A. S.

AU - Loginova, D. O.

PY - 2025/6/4

Y1 - 2025/6/4

N2 - THE AIM OF THE STUDY. To clarify the role of acyl-ghrelin in the development of protein-energy wasting of haemodialysis patients (HD). PATIENTS AND METHODS. A total of 645 patients receiving treatment with programmatic bicarbonate HD for 8.4 ± 5.3 years, including 345 women and 300 men, the average age was 56.8 ± 12.8 years. Nutritional status was assessed using the method proposed by the International Society of Renal Nutrition and Metabolism (ISRNM). For the quantitative determination of acyl-ghrelin, the enzyme-linked immunosorbent assay kit “Active Ghrelin ELISA Kit” (highly sensitive method) from Sceti KK, Japan was used in this work. Reference values: 30-62 fmol/ml. RESULTS. The prevalence of protein-energy wasting (PEM) using the ISRNM method was 24.9% (160 patients). Reduced levels of acyl-ghrelin were detected in 352 patients (54.5%). The average acyl-ghrelin values in patients without signs of PEW were 50.2±10.3 fmol/ml, and in patients with PEW 24.9±9.2 fmol/ml (p

AB - THE AIM OF THE STUDY. To clarify the role of acyl-ghrelin in the development of protein-energy wasting of haemodialysis patients (HD). PATIENTS AND METHODS. A total of 645 patients receiving treatment with programmatic bicarbonate HD for 8.4 ± 5.3 years, including 345 women and 300 men, the average age was 56.8 ± 12.8 years. Nutritional status was assessed using the method proposed by the International Society of Renal Nutrition and Metabolism (ISRNM). For the quantitative determination of acyl-ghrelin, the enzyme-linked immunosorbent assay kit “Active Ghrelin ELISA Kit” (highly sensitive method) from Sceti KK, Japan was used in this work. Reference values: 30-62 fmol/ml. RESULTS. The prevalence of protein-energy wasting (PEM) using the ISRNM method was 24.9% (160 patients). Reduced levels of acyl-ghrelin were detected in 352 patients (54.5%). The average acyl-ghrelin values in patients without signs of PEW were 50.2±10.3 fmol/ml, and in patients with PEW 24.9±9.2 fmol/ml (p

KW - acyl-ghrelin

KW - haemodialysis

KW - protein-energy wasting

UR - https://www.mendeley.com/catalogue/07c835a3-631b-3413-a654-139b7029227d/

U2 - 10.36485/1561-6274-2025-29-2-42-49

DO - 10.36485/1561-6274-2025-29-2-42-49

M3 - статья

VL - 29

SP - 42

EP - 49

JO - Nephrology (Saint-Petersburg)

JF - Nephrology (Saint-Petersburg)

SN - 1561-6274

IS - 2

ER -

ID: 145048310