Частота выявления стеатоза и фиброза печени у жителей Санкт-Петербурга при применении методов транзиентной эластографии и оценки контролируемого параметра затухания ультразвука. / Kovyazina, Veronika P.; Raikhelson, Karina L.; Prashnova, Maria K.; Pazenko, Ekaterina V.; Palgova, Ludmila K.; Kondrashina, Elina A.
In: РОССИЙСКИЙ ЖУРНАЛ ГАСТРОЭНТЕРОЛОГИИ, ГЕПАТОЛОГИИ, КОЛОПРОКТОЛОГИИ, Vol. 31, No. 1, 2021, p. 31-38.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Частота выявления стеатоза и фиброза печени у жителей Санкт-Петербурга при применении методов транзиентной эластографии и оценки контролируемого параметра затухания ультразвука
AU - Kovyazina, Veronika P.
AU - Raikhelson, Karina L.
AU - Prashnova, Maria K.
AU - Pazenko, Ekaterina V.
AU - Palgova, Ludmila K.
AU - Kondrashina, Elina A.
N1 - Ковязина В.П., Райхельсон К.Л., Прашнова М.К., Пазенко Е.В., Пальгова Л.К., Кондрашина Э.А. Частота выявления стеатоза и фиброза печени у жителей Санкт-Петербурга при применении методов транзиентной эластографии и оценки контролируемого параметра затухания ультразвука. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2021;31(1):31-38. https://doi.org/10.22416/1382-4376-2021-31-1-31-38
PY - 2021
Y1 - 2021
N2 - Aim. Estimation of the liver steatosis and fibrosis incidence with transient elastography and the controlled attenuation parameter in residents of St. Petersburg. Materials and methods. A prospective open single-centre population study included history, anthropometric and laboratory data on 318 outpatients aged 24—89 years (mean age 52.6 ± 14.6 years). The degrees of steatosis (assessed with the controlled attenuation parameter as ultrasound amplitude dropdown quantification in liver) and fibrosis were determined with a Fibroscan 502 Touch unit (Echosens, France). Results. Hepatic steatosis of predominantly high degree was revealed in 44.7%, combined fibrosis and steatosis — in 28%; isolated fibrosis of various stage — in 2.5%, no structural changes — in 24.8% individuals. The growth of body mass index and waist circumference significantly correlated in women with pronounced liver changes. Serum transaminase activity increased with more severe liver changes, being statistically significant for aspartic transaminase only. Conclusion. A high incidence of primary liver steatosis and fibrosis in residents of St. Petersburg warrants improved diagnostic algorithms and routine preventive measures. Transient elastography with the controlled attenuation parameter estimation provides a convenient non-invasive screening for hepatic fibrosis and steatosis.
AB - Aim. Estimation of the liver steatosis and fibrosis incidence with transient elastography and the controlled attenuation parameter in residents of St. Petersburg. Materials and methods. A prospective open single-centre population study included history, anthropometric and laboratory data on 318 outpatients aged 24—89 years (mean age 52.6 ± 14.6 years). The degrees of steatosis (assessed with the controlled attenuation parameter as ultrasound amplitude dropdown quantification in liver) and fibrosis were determined with a Fibroscan 502 Touch unit (Echosens, France). Results. Hepatic steatosis of predominantly high degree was revealed in 44.7%, combined fibrosis and steatosis — in 28%; isolated fibrosis of various stage — in 2.5%, no structural changes — in 24.8% individuals. The growth of body mass index and waist circumference significantly correlated in women with pronounced liver changes. Serum transaminase activity increased with more severe liver changes, being statistically significant for aspartic transaminase only. Conclusion. A high incidence of primary liver steatosis and fibrosis in residents of St. Petersburg warrants improved diagnostic algorithms and routine preventive measures. Transient elastography with the controlled attenuation parameter estimation provides a convenient non-invasive screening for hepatic fibrosis and steatosis.
KW - Controlled attenuation parameter
KW - Fibrosis
KW - Non-alcoholic fatty liver disease
KW - Non-alcoholic steatohepatitis
KW - Steatosis
KW - Transient elastography
KW - Controlled attenuation parameter
KW - Fibrosis
KW - Non-alcoholic fatty liver disease
KW - Non-alcoholic steatohepatitis
KW - Steatosis
KW - Transient elastography
UR - http://www.scopus.com/inward/record.url?scp=85119517366&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/a6699c82-6607-31fe-b204-d43a2a715a7b/
U2 - 10.22416/1382-4376-2021-31-1-31-38
DO - 10.22416/1382-4376-2021-31-1-31-38
M3 - статья
AN - SCOPUS:85119517366
VL - 31
SP - 31
EP - 38
JO - РОССИЙСКИЙ ЖУРНАЛ ГАСТРОЭНТЕРОЛОГИИ, ГЕПАТОЛОГИИ, КОЛОПРОКТОЛОГИИ
JF - РОССИЙСКИЙ ЖУРНАЛ ГАСТРОЭНТЕРОЛОГИИ, ГЕПАТОЛОГИИ, КОЛОПРОКТОЛОГИИ
SN - 1382-4376
IS - 1
ER -
ID: 75626716