The problem of changes in brain activity in patients with somatic diseases in connection with the main pathology and due to surgical treatment is of particular importance in regard to an increase in the proportion of the population with cardiovascular diseases. The issue is significant with respect to the challenges of social rehabilitation of patients. The article discusses the results of a study of the cognitive functioning of patients with various cardiovascular diseases at the stage of preparation for high tech operations on the vessels of the heart. In total, 98 patients took part in the study, including 35 patients with chronic heart failure (CHF) III-IV functional classes (FC) (according to the New York Heart Association - NYHA) and systolic dysfunction of the left ventricle (LV), whose average age was 50.97 ± 11.24 years, and 63 patients with coronary heart disease (CHD), the average age was 55.95 ± 5.97. The study was carried out using a psychodiagnostic complex, including clinical, psychological, an