Background. In patients with bone metastases of renal cell cancer (RCC), the search for new prognostic factors affecting survival rates is necessary. Aim. To analyze survival rates and identify prognostic factors in patients with RCC metastases in the bones. Materials and methods. A retrospective analysis of data of 350 patients with bone metastases of RCC treated at the Moscow City Oncologic Hospital No. 62 and the City Clinical Oncologic Dispensary (Saint Petersburg) from 2006 to 2022 was performed. 117 (33.4 %) patients were classified into the group of intermediate prognosis, 169 (48.3 %) - into the group of poor prognosis. The study investigated clinical and morphologic prognostic factors affecting survival rates in patients with bone metastases of RCC. Statistical analysis was performed using Statistica 10.0 software packages (StatSoft, USA) through construction of Kaplan-Meier curves and survival tables, development of a mathematical model of survival. Results and conclusion. 3-year, 5-year overall survival (OS) of patients with RCC bone metastases was 38 % (95 % confidence interval (CI) 33-44) and 23 % (95 % CI 18-28), respectively, with a median OS of 28.3 months (95 % CI 23.6-32.9) (p
Translated title of the contributionAnalysis of survival rates and evaluation of prognostic factors in patients with bone metastases of renal cancer
Original languageRussian
Article number2
Pages (from-to)15-24
Number of pages10
JournalОНКОУРОЛОГИЯ
Volume21
Issue number2
DOIs
StatePublished - 6 Aug 2025

    Research areas

  • bone metastases, overall survival, prognostic factor, renal cell cancer

ID: 142462132