Treatment of patients with Hodgkin's lymphoma includes using of glucocorticosteroids, this leads to decreasing bone mineral density and an increasing risk of low-energy fractures. Patients with Hodgkin's lymphoma can be referred for various methods of radiation diagnostics, including cone-beam computed tomography of the dentoalveolar system for dental indications. At present there is no understanding whether it is possible to use modified computed tomographic indices in cone-beam computed tomography in young patients with Hodgkin's lymphoma to assess the decrease in bone mineral density. Purpose. To evaluate computed tomographic indices in identifying decreased bone mineral density in patients with Hodgkin's lymphoma. Material and methods. Cone-beam computed tomograms with calculation of modified computed tomographic indices and dual-energy X-ray absorptiometry data of 48 patients with Hodgkin's lymphoma were analyzed. CBCT was performed on a Galileos. DXA was performed on a Dexxum osteodensitometer. Cohen's kappa was calculated to assess the reproducibility of the indices. Spearman's coefficient (r) was calculated for correlation analysis. Results. The agreement between the observers for calculating the computed tomography indices, ranged from significant to exact (k>0.78). The computed tomography mandibular index (superi- or) for the group with normal and with reduced bone mineral density values were 0.27±0.03 and 0.25±0.07 respectively; computed tomography mandibular index (inferior): 0.34±0.05 and 0.32±0.08 respectively; computed tomography mental index: 3.73±0.40 and 3.54±0.63 respectively. Computed tomography cortical index: 100% – type I in the group with normal bone mineral density, 17% – type II in the group with reduced bone mineral density. Conclusion. Modified computed tomographic indices in young patients with Hodgkin's lymphoma are well reproducible with high values of agreement between observes. Computed tomography mandibular index (superior) less than 0.25 and computed tomography mental index less than 3.4 in patients with Hodgkin's lymphoma may serve as indirect signs of decreased bone mineral density. If indices below threshold values are detected, this may be an indication for prescribing dual-energy X-ray absorptiometry or quantitative computed tomography. Computed tomography cortical index, computed tomography mandibular index (inferior) are not reliable prognostic indices in detecting bone mineral density decline in young patients with Hodgkin's lymphoma. Cone-beam computed tomography can be a useful tool for screening reduced bone mineral density and osteoporosis in patients with Hodgkin's lymphoma.