Documents

Metagenomic investigation of the intestinal microbiota of rats before and after induction ofdysbiosis by injection of ampicillin and metronidazole revealed an increased population of proteobacteria containing in the cell wall lipopolysaccharides, and reduction of faecalibacteria producing butyrate. A significant dose-dependent effect of these metabolites on the contractile activity of the rectum in vitro system was found, which may explain the change in intestinal motility in dysbiotic conditions.
Translated title of the contributionThe potential effect of endotoxin and butyric acid on the contractile activity of the colon in experimental dysbiosis
Original languageRussian
Title of host publicationЗдоровье — основа человеческого потенциала: проблемы и пути их решения. 2018. Т.13, часть 2
Subtitle of host publicationТруды XIII Всероссийской научно-практической конференции с международным участием
Place of PublicationСПб.
Pages1012 - 1024
StatePublished - 2018
EventXIII Всероссийская конференция "Здоровье - основа человеческого потенциала. Проблемы и пути их решения" - Политехнический университет Петра Великого, Санкт-Петербург, Russian Federation
Duration: 22 Nov 2018 → 24 Dec 2018
Conference number: 13
https://humanpotential.spbstu.ru/conference

Conference

ConferenceXIII Всероссийская конференция "Здоровье - основа человеческого потенциала. Проблемы и пути их решения"
Country/TerritoryRussian Federation
CityСанкт-Петербург
Period22/11/18 → 24/12/18
Internet address

    Scopus subject areas

  • Health Professions(all)

    Research areas

  • Lipopolysaccharide, butyrate, Faecalibacterium sp., Enterobacteriaceae, Smooth muscle cells, contractile activity, rectum

ID: 35932894