This article deals with topical issues of implementation of the prompt fission neutron logging progressive method of studying ore in the stratified infiltration uranium deposits, and presents the examples of its use in the ore objects of the Chu Sarysu ore province. Introducing a reliable method of determining uranium content directly in the boreholes would optimally solve the problem of increasing the efficiency of prospecting, evaluation and exploration works in the stratified infiltration deposits of uranium. One such method is prompt fission neutron logging. Prompt fission neutron logging is one of the modifications of the thermal neutron die-away logging methods and is used for directly determining the level of uranium in wells. Prompt fission neutron logging data allows to select the correct algorithm of uranium content calculation taking into account the geochemical environment, and to unambiguously determine the filter interval for production wells. Refs 9. Figs 5. Tables 1.