The attempt of complex estimation of A.A. Ukhtomsky's views on correlation between physiological and psychological in human nature is made on the basis of his scientific and epistolary heritage complete study. Conceptual reconstruction of A.A. Ukhtomsky's doctrine about uniform biosocial human nature revealing objective patterns in his behavior and psychic organization, moral, creative personality and interpersonal communication formation is carried out. The conducted analysis gives grounds to consider the conception as one of the variants of integral science about a man construction which is based on interdisciplinary approach to a number of problems solving. Prospects of A.A. Ukhtomsky's ideas application for modern scientific researches, for problems of man's early ontogenesis study in particular, are given.