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Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций. / Raskin, G A; Mukhina, M S; Kaurtseva, A S; Andreeva, Yu Yu; Zavalishina, L E; Protasova, A E; Orlova, R V.

In: АРХИВ ПАТОЛОГИИ, Vol. 85, No. 1, 2023, p. 36-42.

Research output: Contribution to journal › Article › peer-review

Harvard

Raskin, GA, Mukhina, MS, Kaurtseva, AS, Andreeva, YY, Zavalishina, LE, Protasova, AE & Orlova, RV 2023, 'Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций', АРХИВ ПАТОЛОГИИ, vol. 85, no. 1, pp. 36-42. https://doi.org/10.17116/patol20238501136

APA

Raskin, G. A., Mukhina, M. S., Kaurtseva, A. S., Andreeva, Y. Y., Zavalishina, L. E., Protasova, A. E., & Orlova, R. V. (2023). Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций. АРХИВ ПАТОЛОГИИ, 85(1), 36-42. https://doi.org/10.17116/patol20238501136

Vancouver

Raskin GA, Mukhina MS, Kaurtseva AS, Andreeva YY, Zavalishina LE, Protasova AE et al. Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций. АРХИВ ПАТОЛОГИИ. 2023;85(1):36-42. https://doi.org/10.17116/patol20238501136

Author

Raskin, G A ; Mukhina, M S ; Kaurtseva, A S ; Andreeva, Yu Yu ; Zavalishina, L E ; Protasova, A E ; Orlova, R V. / Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций. In: АРХИВ ПАТОЛОГИИ. 2023 ; Vol. 85, No. 1. pp. 36-42.

BibTeX

@article{28d93bdbc6ff4251bb6d44f9a184c574,
title = "Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций",
abstract = "Microsatellite instability, which is caused by a deficiency in the DNA unpaired nucleotide repair system, is an important pathogenetic event for some tumors. In addition, the detection of this molecular feature becomes an independent prognostic factor in the course of the disease and a predictor for the appointment of therapy with immune checkpoint inhibitors. Immunohistochemistry is a reliable and available method for detecting a deficiency in the DNA mismatch repair system, and it has recommended as a screening for hereditary syndromes associated with microsatellite instability. This article discusses the advantages and disadvantages of this research method from the point of view of the practitioner.",
keywords = "Microsatellite Instability, DNA, Neoplastic Syndromes, Hereditary, Microsatellite Repeats, Humans, Colorectal Neoplasms/pathology, Brain Neoplasms/genetics",
author = "Raskin, {G A} and Mukhina, {M S} and Kaurtseva, {A S} and Andreeva, {Yu Yu} and Zavalishina, {L E} and Protasova, {A E} and Orlova, {R V}",
year = "2023",
doi = "10.17116/patol20238501136",
language = "русский",
volume = "85",
pages = "36--42",
journal = "АРХИВ ПАТОЛОГИИ",
issn = "0004-1955",
publisher = "Медиа Сфера",
number = "1",

}

RIS

TY - JOUR

T1 - Определение микросателлитной нестабильности и состояния генов репарации неспаренных нуклеотидов ДНК при опухолях различных локализаций

AU - Raskin, G A

AU - Mukhina, M S

AU - Kaurtseva, A S

AU - Andreeva, Yu Yu

AU - Zavalishina, L E

AU - Protasova, A E

AU - Orlova, R V

PY - 2023

Y1 - 2023

N2 - Microsatellite instability, which is caused by a deficiency in the DNA unpaired nucleotide repair system, is an important pathogenetic event for some tumors. In addition, the detection of this molecular feature becomes an independent prognostic factor in the course of the disease and a predictor for the appointment of therapy with immune checkpoint inhibitors. Immunohistochemistry is a reliable and available method for detecting a deficiency in the DNA mismatch repair system, and it has recommended as a screening for hereditary syndromes associated with microsatellite instability. This article discusses the advantages and disadvantages of this research method from the point of view of the practitioner.

AB - Microsatellite instability, which is caused by a deficiency in the DNA unpaired nucleotide repair system, is an important pathogenetic event for some tumors. In addition, the detection of this molecular feature becomes an independent prognostic factor in the course of the disease and a predictor for the appointment of therapy with immune checkpoint inhibitors. Immunohistochemistry is a reliable and available method for detecting a deficiency in the DNA mismatch repair system, and it has recommended as a screening for hereditary syndromes associated with microsatellite instability. This article discusses the advantages and disadvantages of this research method from the point of view of the practitioner.

KW - Microsatellite Instability

KW - DNA

KW - Neoplastic Syndromes, Hereditary

KW - Microsatellite Repeats

KW - Humans

KW - Colorectal Neoplasms/pathology

KW - Brain Neoplasms/genetics

U2 - 10.17116/patol20238501136

DO - 10.17116/patol20238501136

M3 - статья

C2 - 36785960

VL - 85

SP - 36

EP - 42

JO - АРХИВ ПАТОЛОГИИ

JF - АРХИВ ПАТОЛОГИИ

SN - 0004-1955

IS - 1

ER -

ID: 152250468