TY - JOUR

T1 - НЕОБХОДИМОСТЬ ИНДИВИДУАЛЬНОГО ПОДБОРА ПРОБИОТИКОВ, СОДЕРЖАЩИХ ЛАКТОБАЦИЛЫ И ЭНТЕРОКОККИ ДЛЯ ПОВЫШЕНИЯ ЭФФЕКТИВНОСТИ ТЕРАПИИ КАМПИЛОБАКТЕРИОЗА

AU - Ермоленко, Константин

AU - Болдырева, Надежда Павловна

AU - Мартенс, Эльвира

AU - Железова, Людмила

AU - Сидоренко, Сергей

AU - Суворов, Александр Николаевич

AU - Ермоленко, Е. И.

PY - 2021/4/7

Y1 - 2021/4/7

N2 - The article highlights the problem of improving the rational treatment of campylobacteriosis. Probiotics are present in treatment regimens along with antibiotics, which have the advantage that they do not violate intestinal microbiocenosis and provide the ability to correct dysbiotic conditions. As well as antimicrobial agents, probiotics have different effects on the growth of pathogenic microorganisms. Campylobacter spp. probiotics in the in vitro system. The article studies the anticampylobacter activity of probiotic cultures of Enterococcus faecium L3, Lactobacillus plantarum 8 R-A3, a mixture of Lactobacillus acidophilus and Saccharomyces boulardii by two-layer agar and droplet method. Analysis of the antagonistic activity of chemically synthesized bacteriocins. The high sensitivity of Campylobacter spp was presented. to probiotics having lactobacilli and enterococci, as well as their metabolites (including bacteriocins). The strain-specific activity of probiotics and its dependence on their ability to produce bacteriocins were found. The results and data of other researchers indicate the need for individual selection of probiotics for the treatment of campylobacteriosis, the feasibility of analyzing the bacteriocinogenicity of the strains and testing their effect on the growth of clinical isolates.

AB - The article highlights the problem of improving the rational treatment of campylobacteriosis. Probiotics are present in treatment regimens along with antibiotics, which have the advantage that they do not violate intestinal microbiocenosis and provide the ability to correct dysbiotic conditions. As well as antimicrobial agents, probiotics have different effects on the growth of pathogenic microorganisms. Campylobacter spp. probiotics in the in vitro system. The article studies the anticampylobacter activity of probiotic cultures of Enterococcus faecium L3, Lactobacillus plantarum 8 R-A3, a mixture of Lactobacillus acidophilus and Saccharomyces boulardii by two-layer agar and droplet method. Analysis of the antagonistic activity of chemically synthesized bacteriocins. The high sensitivity of Campylobacter spp was presented. to probiotics having lactobacilli and enterococci, as well as their metabolites (including bacteriocins). The strain-specific activity of probiotics and its dependence on their ability to produce bacteriocins were found. The results and data of other researchers indicate the need for individual selection of probiotics for the treatment of campylobacteriosis, the feasibility of analyzing the bacteriocinogenicity of the strains and testing their effect on the growth of clinical isolates.

KW - Bacteriocins

KW - Campylobacteriosis

KW - Enterococci

KW - Lactobacilli

KW - Probiotics

KW - Bacteriocins

KW - Campylobacteriosis

KW - Enterococci

KW - Lactobacilli

KW - Probiotics

UR - http://www.scopus.com/inward/record.url?scp=85106858015&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/23a5e5c5-b067-3124-a7a7-43f0edc0bbbe/

U2 - 10.31146/1682-8658-ecg-186-2-88-93

DO - 10.31146/1682-8658-ecg-186-2-88-93

M3 - статья

VL - 185

SP - 88

EP - 93

JO - Experimental and Clinical Gastroenterology

JF - Experimental and Clinical Gastroenterology

SN - 1682-8658

IS - 2

ER -