Summary Aims: to study comorbid mental disorders, psychological characteristics and quality of life of patients with hypertension. Methods: 50 patients with hypertension at the age of 60.8 + 1.5 years were examined. Methods of clinical and scaling assessment and statistical methods were used. Results. Mental disorders in 53% of cases corresponded to a moderate degree of severity, among them 87% were recurrent depressive disorders, represented mainly by anxiety-depressive syndrome, and 13% were generalized anxiety disorders with a predominance of somatized anxiety. More than half of the patients experienced longer and more severe attacks of depression with age. The most frequent were emotive, cyclothymic and anxious types. The greatest number of complications of hypertension was found among patients with anxious (73%) and demonstrative (70%) types. A decrease in the quality of life in patients with hypertension has been established, which is mediated by anxious personality traits and the severity of depression. Conclusion. Patients with hypertension are characterized by moderate, mainly anxiety-depressive disorders, somatized anxiety, emotive, cyclothymic and anxious personality types, reduced quality of life, primarily due to the assessment of health and well-being with sufficient satisfaction with intellectual, physical and daily activity. Personality characteristics of patients mediate the level of quality of life and the severity of hypertension. The quality of life of patients with hypertension is also mediated by the severity of depression.