TY - JOUR

T1 - Клинические и структурно-функциональные особенности пароксизмальных расстройств, обусловленных опухолями островковой и височной долей

AU - Хачатрян, Р. Г.

AU - Барт, В. А.

AU - Маслова, Л. Н.

AU - Фадеева, Т. Н.

AU - Себелев, К. И.

AU - Тастанбеков, М. М.

AU - Алексеева, Т. М.

AU - Хачатрян, В. А.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - OBJECTIVE: To analyze the characteristics of paroxysmal syndrome in insular and temporal lobe tumors, to determine their relationship with the histological structure of tumor, to assess the effect of tumor growth nature on severity of disease. MATERIAL AND METHODS: A retrospective analysis enrolled 80 patients aged 11 - 80 years with insular and temporal lobe tumors and symptomatic epilepsy. All patients underwent surgery at the Polenov National Research Neurosurgery Center in Almazov National Medical Research Center for the period from 2012 to 2018. RESULTS: The main group consisted of 29 patients with tumors of temporal and insular lobes. Control group of 51 patients with temporal gliomas was formed for comparative analysis. It was found that involvement of insular lobe into paroxysmal syndrome is characterized by attacks with a motor component, somatosensory paroxysms, vegetative manifestations (respiratory attacks, salivation, nausea), speech disorders and taste hallucinations. Derealization, motor arrest and déjà vu/jamis vu paroxysms were more common in patients with temporal lobe lesion. Neoplastic lesion of the insular lobe shortens the period between manifestation of paroxysms and surgical treatment. Moreover, this type of disease is characterized by higher incidence of seizures compared to isolated temporal lobe tumors.

AB - OBJECTIVE: To analyze the characteristics of paroxysmal syndrome in insular and temporal lobe tumors, to determine their relationship with the histological structure of tumor, to assess the effect of tumor growth nature on severity of disease. MATERIAL AND METHODS: A retrospective analysis enrolled 80 patients aged 11 - 80 years with insular and temporal lobe tumors and symptomatic epilepsy. All patients underwent surgery at the Polenov National Research Neurosurgery Center in Almazov National Medical Research Center for the period from 2012 to 2018. RESULTS: The main group consisted of 29 patients with tumors of temporal and insular lobes. Control group of 51 patients with temporal gliomas was formed for comparative analysis. It was found that involvement of insular lobe into paroxysmal syndrome is characterized by attacks with a motor component, somatosensory paroxysms, vegetative manifestations (respiratory attacks, salivation, nausea), speech disorders and taste hallucinations. Derealization, motor arrest and déjà vu/jamis vu paroxysms were more common in patients with temporal lobe lesion. Neoplastic lesion of the insular lobe shortens the period between manifestation of paroxysms and surgical treatment. Moreover, this type of disease is characterized by higher incidence of seizures compared to isolated temporal lobe tumors.

KW - epilepsy surgery

KW - insular epilepsy

KW - insular glioma

KW - temporal lobe epilepsy

KW - Humans

KW - Middle Aged

KW - Temporal Lobe/diagnostic imaging

KW - Cerebral Cortex

KW - Electroencephalography

KW - Epilepsy, Temporal Lobe/surgery

KW - Young Adult

KW - Magnetic Resonance Imaging

KW - Glioma

KW - Adolescent

KW - Aged, 80 and over

KW - Adult

KW - Aged

KW - Retrospective Studies

KW - Child

KW - Supratentorial Neoplasms

KW - Epilepsy surgery

KW - Insular epilepsy

KW - Insular glioma

KW - Temporal lobe epilepsy

UR - http://www.scopus.com/inward/record.url?scp=85089170464&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ce25addd-f4fb-3f04-9263-1a13bdec7ec5/

U2 - 10.17116/neiro20208404136

DO - 10.17116/neiro20208404136

M3 - статья

C2 - 32759925

AN - SCOPUS:85089170464

VL - 84

SP - 36

EP - 45

JO - ЖУРНАЛ ВОПРОСЫ НЕЙРОХИРУРГИИ ИМ. Н.Н. БУРДЕНКО

JF - ЖУРНАЛ ВОПРОСЫ НЕЙРОХИРУРГИИ ИМ. Н.Н. БУРДЕНКО

SN - 0042-8817

IS - 4

ER -