ФАРМАКОЛОГИЧЕСКАЯ ПРОФИЛАКТИКА РЕПЕРФУЗИОННОГО СИНДРОМА У ПОСТРАДАВШИХ С ТЯЖЁЛЫМИ СОЧЕТАННЫМИ ТРАВМАМИ, СОПРОВОЖДАЮЩИМИСЯ ШОКОМ. / Polushin, I. S.; Shakh, B. N.; Teplov, V. M.; Smirnov, D. B.; Komedev, S. S.
In: Vestnik khirurgii imeni I. I. Grekova, Vol. 172, No. 5, 2013, p. 41-45.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - ФАРМАКОЛОГИЧЕСКАЯ ПРОФИЛАКТИКА РЕПЕРФУЗИОННОГО СИНДРОМА У ПОСТРАДАВШИХ С ТЯЖЁЛЫМИ СОЧЕТАННЫМИ ТРАВМАМИ, СОПРОВОЖДАЮЩИМИСЯ ШОКОМ
AU - Polushin, I. S.
AU - Shakh, B. N.
AU - Teplov, V. M.
AU - Smirnov, D. B.
AU - Komedev, S. S.
PY - 2013
Y1 - 2013
N2 - A comparative assessment of buffer activity of reamberin and polyoxyfumaren was made. Their influence on systemic consumption of oxygen, content of lactate in blood, parameters of central hemodynamics were followed. The research includes 44 victims (aged 25-70 years) with severe shockogenic injuries. Reamberin was included in composition of fluid therapy of I group (n=30)and polyoxyfumaren was used in 11 group (n=14). Parameters of acid-base balance of arterial blood, VO2, VCO,, contents of lactate in mixed venous blood, parameters of central hemodynamics were measured in monitor regimen before the infusion. It was proved, that the intravenous infusion of reamberin and polyoxyfumaren accompanied by reliable rise of minute consumption of oxygen (27 and 18% respectively). The drugs decrease the lactate level in blood, reliably increase buffer capacity of blood, correct the metabolic acidosis. Both antihy-poxanthines allow the increase of minute volume of circulation: reamberin on 15%, polyoxyfumaren on 34,9%. The volemic effect of polyoxyfumaren resulted in the increase of circular plasma volume after finishing the infusion on 49,5%, in the case of reamberin - on 16%.
AB - A comparative assessment of buffer activity of reamberin and polyoxyfumaren was made. Their influence on systemic consumption of oxygen, content of lactate in blood, parameters of central hemodynamics were followed. The research includes 44 victims (aged 25-70 years) with severe shockogenic injuries. Reamberin was included in composition of fluid therapy of I group (n=30)and polyoxyfumaren was used in 11 group (n=14). Parameters of acid-base balance of arterial blood, VO2, VCO,, contents of lactate in mixed venous blood, parameters of central hemodynamics were measured in monitor regimen before the infusion. It was proved, that the intravenous infusion of reamberin and polyoxyfumaren accompanied by reliable rise of minute consumption of oxygen (27 and 18% respectively). The drugs decrease the lactate level in blood, reliably increase buffer capacity of blood, correct the metabolic acidosis. Both antihy-poxanthines allow the increase of minute volume of circulation: reamberin on 15%, polyoxyfumaren on 34,9%. The volemic effect of polyoxyfumaren resulted in the increase of circular plasma volume after finishing the infusion on 49,5%, in the case of reamberin - on 16%.
UR - http://www.scopus.com/inward/record.url?scp=84898888664&partnerID=8YFLogxK
M3 - статья
C2 - 24640747
AN - SCOPUS:84898888664
VL - 172
SP - 41
EP - 45
JO - ВЕСТНИК ХИРУРГИИ ИМ. И.И. ГРЕКОВА
JF - ВЕСТНИК ХИРУРГИИ ИМ. И.И. ГРЕКОВА
SN - 0042-4625
IS - 5
ER -
ID: 85790319