The paper presents new geochronological results on pitchblende from Tuyukan ore cluster in the Tonod district by U-Pb ID-TIMS technique. It has been established that the age of uranium-bearing veins with the richest mineralization is 1234 ± 12 Ma. The conclusion is made about the stage-by-stage hydrothermal uranium ore process with the formation of telescoped polychronous ores in the Tuyukan deposit and later (Riphean) pitchblende veins in its flanks. The latter environment as independent one was first characterized and dated in the Natalie ore occurrence.