TY - JOUR

T1 - ВЛИЯНИЕ КОГНИТИВНЫХ НАРУШЕНИЙ ПРИ РЕКУРРЕНТНОЙ ДЕПРЕССИИ НА СОЦИАЛЬНОЕ ФУНКЦИОНИРОВАНИЕ БОЛЬНЫХ В РЕМИССИИ

AU - Гвоздецкий, А.Н.

AU - Петрова, Н.Н.

AU - Акулин, И.М.

PY - 2019

Y1 - 2019

N2 - Despite the fact that many patients with recurrent depression achieve remission state, the patients are not socially adopted. Authors suggest that the severity of cognitive deficits predicts the decrease in social functioning in patients with major depression in remission state. The study aimed on revealing which cognitive functions mainly influence on different aspects of social functioning in the group. Seventeen patients with major depression were included in the study, of which 58,6% corresponded to full-remission criteria (they had less than 10 points as per Montgomery-Asberg Depression Rating Scale (MADRS)). The social functioning was assessed by using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). All patients performed cognitive testing by using the Brief Assessment of Cognition in Affective disorders battery (BAC-A). All patients demonstrated social disability (more than 5% on all WHODAS 2.0 subscales): in 1-2 domains - 12,9%, in 3-4 domains - 25,7%, in 5 and 6 domains - 61,4%. In comparison with partly remitted patients, patients in the full remission state had higher social functioning (p<0,01). Deficit in response inhibition influenced on patients ability to concentrate and to make decisions (p=0,007). The speed of processes influenced on quality of everyday functioning (p=0,02) and theirs participation in social activities (p=0,007). Verbal learning function was also associated with participation in social activities (p=0,02). Thus, beyond the achievement of full remission in patients with major depressive disorder, it is necessary to restore cognitive functions including response inhibition, speed of processes and verbal learning. These steps are important in patients recovery to premorbid level.

AB - Despite the fact that many patients with recurrent depression achieve remission state, the patients are not socially adopted. Authors suggest that the severity of cognitive deficits predicts the decrease in social functioning in patients with major depression in remission state. The study aimed on revealing which cognitive functions mainly influence on different aspects of social functioning in the group. Seventeen patients with major depression were included in the study, of which 58,6% corresponded to full-remission criteria (they had less than 10 points as per Montgomery-Asberg Depression Rating Scale (MADRS)). The social functioning was assessed by using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). All patients performed cognitive testing by using the Brief Assessment of Cognition in Affective disorders battery (BAC-A). All patients demonstrated social disability (more than 5% on all WHODAS 2.0 subscales): in 1-2 domains - 12,9%, in 3-4 domains - 25,7%, in 5 and 6 domains - 61,4%. In comparison with partly remitted patients, patients in the full remission state had higher social functioning (p<0,01). Deficit in response inhibition influenced on patients ability to concentrate and to make decisions (p=0,007). The speed of processes influenced on quality of everyday functioning (p=0,02) and theirs participation in social activities (p=0,007). Verbal learning function was also associated with participation in social activities (p=0,02). Thus, beyond the achievement of full remission in patients with major depressive disorder, it is necessary to restore cognitive functions including response inhibition, speed of processes and verbal learning. These steps are important in patients recovery to premorbid level.

KW - РЕКУРРЕНТНАЯ ДЕПРЕССИЯ

KW - ремиссия

KW - когнитивные функции

KW - социальное функционирование

KW - восстановление

KW - major depression

KW - Remission

KW - cognition

KW - SOCIAL PERFORMANCE

KW - RECOVERY

UR - https://psychiatr.ru/magazine/scp/104

UR - https://www.elibrary.ru/item.asp?id=37342040

M3 - статья

VL - 29

SP - 5

EP - 9

JO - СОЦИАЛЬНАЯ И КЛИНИЧЕСКАЯ ПСИХИАТРИЯ

JF - СОЦИАЛЬНАЯ И КЛИНИЧЕСКАЯ ПСИХИАТРИЯ

SN - 0869-4893

IS - 1

ER -