Objective - to study the characteristics of cytoarchitecture and chemoarchitecture of the subicular complex in the human fetal brain. Material and methods. Ten hemispheres of human fetal brain were studied at 20-26 weeks of gestation. The material was obtained from the archive of the Department of Pathological Anatomy with a Course of Forensic Medicine of St. Petersburg State Pediatric Medical University. Histological paraffin sections were stained according to Nissl method, and immunohistochemically with antibodies raised against the layer-specific proteins SATB2, FOXP1, CTIP2, TBR1. Results. The deep layers (py, po, V, VI) of the subicular complex, which includes subiculum, presubiculum and parasubiculum, contained FOXP1 / CTIP2 and TBR1 immunopositive neurons, and the superficial layers (II, III) contained SATB2positive cells. Conclusions. Subiculum demonstrates the features of two cortical formations: the allocortex (the layer of FOXP1+/CTIP2+ cells, the absence of lamina dissecans) and the periallocortex
Original languageRussian
Pages (from-to)14-17
JournalМорфология
Volume156
Issue number4
StatePublished - 2019

    Research areas

  • layer-specific proteins, Parasubiculum, Presubiculum, subiculum, парасубикулюм, пресубикулюм, слой-специфичные белки, субикулюм

ID: 78377984