Research output: Contribution to journal › Article › peer-review
ИНТРАКОРОНАРНОЕ ПРИМЕНЕНИЕ ЛЕВОКАРНИТИНА ПРИ СТЕНТИРОВАНИИ КОРОНАРНЫХ АРТЕРИЙ У ПАЦИЕНТОВ ВЫСОКОГО РИСКА. / Семиголовский, Никита Юрьевич; Баллюзек, Марина Феликсовна; Гуслев, Александр Борисович; Мазуренко, Сергей Олегович; Козаев, Андрей Викентиевич; Семенова, Ирина Германовна; Никольская, Елена Михайловна; Щеглов, А.Н.
In: Медицина экстремальных ситуаций, Vol. 26, No. 1, 01.03.2024, p. 106-111.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - ИНТРАКОРОНАРНОЕ ПРИМЕНЕНИЕ ЛЕВОКАРНИТИНА ПРИ СТЕНТИРОВАНИИ КОРОНАРНЫХ АРТЕРИЙ У ПАЦИЕНТОВ ВЫСОКОГО РИСКА
AU - Семиголовский, Никита Юрьевич
AU - Баллюзек, Марина Феликсовна
AU - Гуслев, Александр Борисович
AU - Мазуренко, Сергей Олегович
AU - Козаев, Андрей Викентиевич
AU - Семенова, Ирина Германовна
AU - Никольская, Елена Михайловна
AU - Щеглов, А.Н.
PY - 2024/3/1
Y1 - 2024/3/1
N2 - The main causes of postoperative mortality associated with percutaneous coronary interventions involving the coronary artery stent insertion are perioperative myocardial infarction and acute heart failure due to inadequate protection of the myocardium against ischemia/reperfusion. The standard therapy includes beta blockers, anticoagulants, antiplatelet drugs. Two clinical cases of successful use of intravenous levocarnitine for cardioprotection in senile patients with acute forms of coronary heart disease with multivessel lesions are reported. The postoperative period went well, smooth dynamics of biomarker levels (troponin I, creatine phosphokinase, MB fraction of creatine phosphokinase) was observed, and ischemic ECG changes were relatively small. The expected results of the technique application include reduction of intraoperative and postoperative complications of ischemia/reperfusion and the increase in effectiveness of the stent insertion clinical outcomes in high-risk patients
AB - The main causes of postoperative mortality associated with percutaneous coronary interventions involving the coronary artery stent insertion are perioperative myocardial infarction and acute heart failure due to inadequate protection of the myocardium against ischemia/reperfusion. The standard therapy includes beta blockers, anticoagulants, antiplatelet drugs. Two clinical cases of successful use of intravenous levocarnitine for cardioprotection in senile patients with acute forms of coronary heart disease with multivessel lesions are reported. The postoperative period went well, smooth dynamics of biomarker levels (troponin I, creatine phosphokinase, MB fraction of creatine phosphokinase) was observed, and ischemic ECG changes were relatively small. The expected results of the technique application include reduction of intraoperative and postoperative complications of ischemia/reperfusion and the increase in effectiveness of the stent insertion clinical outcomes in high-risk patients
KW - acute coronary syndrome
KW - coronary heart disease
KW - intracoronary administration
KW - ischemia/reperfusion
KW - levocarnitine
KW - myocardial infarction
KW - percutaneous coronary interventions
UR - https://mes.fmba.press/files/issues/mes.fmba.press/2024/1/2024-1-1424_ru.pdf?lang=ru&ysclid=m2unnkxy76503065381
UR - https://www.mendeley.com/catalogue/6f5ea8f7-f799-319c-a900-e3434f32303f/
U2 - 10.47183/mes.2024.010
DO - 10.47183/mes.2024.010
M3 - статья
VL - 26
SP - 106
EP - 111
JO - Медицина экстремальных ситуаций
JF - Медицина экстремальных ситуаций
SN - 2306-6326
IS - 1
ER -
ID: 126520482